Evidence map›Paper›PMID 26355041›Full record

ArticleScientific reports2015

The severity of initial acute kidney injury at admission of geriatric patients significantly correlates with subsequent in-hospital complications.

Chia-Ter Chao, Hung-Bin Tsai, Chia-Yi Wu, Yu-Feng Lin, Nin-Chieh Hsu, Jin-Shing Chen, Kuan-Yu Hung

Abstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Readmission and Mortality After Hospitalization With Acute Kidney Injury.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
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  15. Article
  16. Article
  17. Article
  18. Observational
  19. Acute kidney injury and aging.Pediatric nephrology (Berlin, Germany) · 2021
    Review
  20. [Prognosis of in hospital nonagenarians with acute kidney injury].Anales del sistema sanitario de Navarra · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chia-Ter ChaoDepartment of Medicine, National Taiwan University Hospital Jin-Shan branch, New Taipei City, Taiwan.
Hung-Bin TsaiTraumatology, National Taiwan University Hospital, Taipei, Taiwan.
Chia-Yi WuThe Department of Nursing, National Taiwan University, Taipei, Taiwan.
Yu-Feng LinTraumatology, National Taiwan University Hospital, Taipei, Taiwan.
Nin-Chieh HsuTraumatology, National Taiwan University Hospital, Taipei, Taiwan.
Jin-Shing ChenTraumatology, National Taiwan University Hospital, Taipei, Taiwan.
Kuan-Yu HungDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is associated with higher hospital mortality. However, the relationship between geriatric AKI and in-hospital complications is unclear. We prospectively enrolled elderly patients (≥65 years) from general medical wards of National Taiwan University Hospital, part of whom presented AKI at admission. We recorded subsequent in-hospital complications, including catastrophic events, incident gastrointestinal bleeding, hospital-associated infections, and new-onset electrolyte imbalances. Regression analyses were utilized to assess the associations between in-hospital complications and the initial AKI severity. A total of 163 elderly were recruited, with 39% presenting AKI (stage 1: 52%, stage 2: 23%, stage 3: 25%). The incidence of any in-hospital complication was significantly higher in the AKI group than in the non-AKI group (91% vs. 68%, p < 0.01). Multiple regression analyses indicated that elderly patients presenting with AKI had significantly higher risk of developing any complication (Odds ratio [OR] = 3.51, p = 0.01) and new-onset electrolyte imbalance (OR = 7.1, p < 0.01), and a trend toward more hospital-associated infections (OR = 1.99, p = 0.08). The risk of developing complications increased with higher AKI stage. In summary, our results indicate that initial AKI at admission in geriatric patients significantly increased the risk of in-hospital complications.

Indexed as

Geriatric AssessmentAcid-Base ImbalanceAcute Kidney InjuryAgedAged, 80 and overComorbidityFemaleHospital MortalityHumansIncidenceMalePatient AdmissionPatient Outcome AssessmentRisk FactorsSeverity of Illness IndexTaiwan

Identifiers

PMID26355041
PMCPMC4564739

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.