Evidence map›Paper›PMID 26354894›Full record

ReviewCold Spring Harbor perspectives in biology2015

The Nodes of Ranvier: Molecular Assembly and Maintenance.

Matthew N Rasband, Elior Peles

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Journal of Zhejiang University. Science. B · 2025
    Review
  9. Nodal NaFrontiers in cellular neuroscience · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Glial Regulation of Circuit Wiring, Firing, and Expiring in theCold Spring Harbor perspectives in biology · 2024
    Review
  14. Article
  15. Oligodendrocytes: Myelination, Plasticity, and Axonal Support.Cold Spring Harbor perspectives in biology · 2024
    Review
  16. Peripheral Nervous System (PNS) Myelin Diseases.Cold Spring Harbor perspectives in biology · 2024
    Review
  17. Article
  18. Article
  19. Motor Activity-Induced White Matter Repair in White Matter Stroke.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  20. Article

45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matthew N RasbandDepartment of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.
Elior PelesDepartment of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot 76100, Israel.

Funding

Neuroglial Interactions at the Node of RanvierR01NS044916 · NINDS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RASBAND, MATTHEW N · 2002 to 2020
$4.2M
Mechanisms of CNS node of Ranvier formation.R01NS069688 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI RASBAND, MATTHEW N · 2010 to 2019
$3.4M
Neuroglial interactions at the node of RanvierR37NS044916 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI RASBAND, MATTHEW N · 2012 to 2018
$2.9M
Role of three novel CAMs in myelinating gliaR01NS050220 · NINDS · WEIZMANN INSTITUTE OF SCIENCE · PI PELES, ELIOR · 2005 to 2015
$1.6M
NINDS NIH HHS NS044916NINDS NIH HHS NS069688NINDS NIH HHS NS50220NINDS NIH HHS R01 NS044916NINDS NIH HHS R01 NS050220NINDS NIH HHS R01 NS069688NINDS NIH HHS R37 NS044916
6 · The paper itself

Abstract

Action potential (AP) propagation in myelinated nerves requires clustered voltage gated sodium and potassium channels. These channels must be specifically localized to nodes of Ranvier where the AP is regenerated. Several mechanisms have evolved to facilitate and ensure the correct assembly and stabilization of these essential axonal domains. This review highlights the current understanding of the axon intrinsic and glial extrinsic mechanisms that control the formation and maintenance of the nodes of Ranvier in both the peripheral nervous system (PNS) and central nervous system (CNS).

Indexed as

Action PotentialsAxonsCentral Nervous SystemModels, BiologicalNerve Fibers, MyelinatedPeripheral Nervous SystemRanvier's NodesSynaptic Transmission

Identifiers

PMID26354894
PMCPMC4772103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.