Evidence map›Paper›PMID 26354812›Full record

ArticleJournal of clinical microbiology2015

Infection with Toxin A-Negative, Toxin B-Negative, Binary Toxin-Positive Clostridium difficile in a Young Patient with Ulcerative Colitis.

Grace O Androga, Julie Hart, Niki F Foster, Adrian Charles, David Forbes, Thomas V Riley

Abstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. An Update onToxins · 2022
    Review
  5. Frontiers in antibiotic alternatives forWorld journal of gastroenterology · 2021
    Article
  6. World journal of hepatology · 2021
    Article
  7. Gut Microbiota and Diarrhea: An Updated Review.Frontiers in cellular and infection microbiology · 2021
    Review
  8. Review
  9. Virulence of new variant strains ofNew microbes and new infections · 2019
    Article
  10. Article
  11. Clostridium difficile infection: review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Review
  12. Article
  13. Review
  14. Current knowledge on the laboratory diagnosis ofWorld journal of gastroenterology · 2017
    Review
  15. Article
  16. Clostridium difficile infection.Nature reviews. Disease primers · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Grace O AndrogaSchool of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Julie HartDepartment of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia.
Niki F FosterSchool of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia.
Adrian CharlesPrincess Margaret Hospital for Children, Subiaco, Western Australia, Australia.
David ForbesPrincess Margaret Hospital for Children, Subiaco, Western Australia, Australia School of Paediatrics and Child Health, The University of Western Australia, Crawley, Western Australia, Australia.
Thomas V RileySchool of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia thomas.riley@uwa.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large clostridial toxin-negative, binary toxin-positive (A(-) B(-) CDT(+)) strains of Clostridium difficile are almost never associated with clinically significant C. difficile infection (CDI), possibly because such strains are not detected by most diagnostic methods. We report the isolation of an A(-) B(-) CDT(+) ribotype 033 (RT033) strain of C. difficile from a young patient with ulcerative colitis and severe diarrhea.

Indexed as

AdolescentADP Ribose TransferasesAnti-Bacterial AgentsAustraliaBacterial ProteinsBacterial ToxinsClostridioides difficileColitis, UlcerativeEnterocolitis, PseudomembranousEnterotoxinsFecesHumansMaleMicrobial Sensitivity TestsRecurrenceactin-specific ADP-ribosyltransferase, ClostridiumADP Ribose TransferasesAnti-Bacterial AgentsBacterial ProteinsBacterial ToxinsEnterotoxinstcdA protein, Clostridium difficiletoxB protein, Clostridium difficile

Identifiers

PMID26354812
PMCPMC4609731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.