Evidence map›Paper›PMID 26354726›Full record

ReviewThe Journal of pathology2016

Cross-species models of human melanoma.

Louise van der Weyden, E Elizabeth Patton, Geoffrey A Wood, Alastair K Foote, Thomas Brenn, Mark J Arends, David J Adams

Abstract readReview
In one paragraph

Review in The Journal of pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. E-Cadherin Immunostaining in Equine Melanocytic Tumors.Animals : an open access journal from MDPI · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Spontaneous and Induced Animal Models for Cancer Research.Diagnostics (Basel, Switzerland) · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Louise van der WeydenExperimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.
E Elizabeth PattonMRC Human Genetics Unit, The MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK.
Geoffrey A WoodDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, 50 Stone Road E, Guelph, Ontario, N1G 2W1, Canada.
Alastair K FooteRossdales Equine Hospital, Cotton End Road, Exning, Newmarket, Suffolk, CB8 7NN, UK.
Thomas BrennPathology Department, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK.
Mark J ArendsCentre for Comparative Pathology, University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh, EH4 2XR, UK.
David J AdamsExperimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.

Funding

Cancer Research UK 14356Medical Research Council MC_PC_U127585840Medical Research Council MC_U127585840Medical Research Council MR/N005902/1Wellcome Trust
6 · The paper itself

Abstract

Although transformation of melanocytes to melanoma is rare, the rapid growth, systemic spread, as well as the chemoresistance of melanoma present significant challenges for patient care. Here we review animal models of melanoma, including murine, canine, equine, and zebrafish models, and detail the immense contribution these models have made to our knowledge of human melanoma development, and to melanocyte biology. We also highlight the opportunities for cross-species comparative genomic studies of melanoma to identify the key molecular events that drive this complex disease.

Indexed as

Disease Models, AnimalAnimalsCell Line, TumorDisease ProgressionDogsGenetic Predisposition to DiseaseGenomeHorsesHumansMelanomaMiceMice, TransgenicMutationNeoplasm TransplantationSkin NeoplasmsTransplantation, Heterologouscross-species analysisgenome analysismelanoma

Identifiers

PMID26354726
PMCPMC4832391

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.