Evidence map›Paper›PMID 26354601›Full record

ReviewBMC medicine2015

Improving health outcomes through concurrent HIV program scale-up and health system development in Rwanda: 20 years of experience.

Sabin Nsanzimana, Krishna Prabhu, Haley McDermott, Etienne Karita, Jamie I Forrest, Peter Drobac, Paul Farmer, Edward J Mills, Agnes Binagwaho

Abstract readReview
In one paragraph

Review in BMC medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
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  11. From tragedy to triumph: Rwanda's healthcare over three decades.Annals of medicine and surgery (2012) · 2025
    Article
  12. Review
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  20. Obstetric admissions and outcomes in an intensive care unit in Malawi.International journal of obstetric anesthesia · 2019
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sabin NsanzimanaInstitute of HIV Disease Prevention and Control, Rwanda Biomedical Centre, Kigali, Rwanda. nsabinco@gmail.com.
Krishna PrabhuHarvard University Medical School, Boston, USA.
Haley McDermottPartners in Health, Boston, USA.
Etienne KaritaProject San Francisco, Kigali, Rwanda.
Jamie I ForrestSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Peter DrobacPartners in Health, Boston, USA.
Paul FarmerHarvard University Medical School, Boston, USA.
Edward J MillsGlobal Evaluative Sciences, Vancouver, Canada.
Agnes BinagwahoHarvard University Medical School, Boston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 1994 genocide against the Tutsi destroyed the health system in Rwanda. It is impressive that a small country like Rwanda has advanced its health system to the point of now offering near universal health insurance coverage. Through a series of strategic structural changes to its health system, catalyzed through international assistance, Rwanda has demonstrated a commitment towards improving patient and population health indicators. In particular, the rapid scale up of antiretroviral therapy (ART) has become a great success story for Rwanda. The country achieved universal coverage of ART at a CD4 cell count of 200 cells/mm(3) in 2007 and increased the threshold for initiation of ART to ≤350 cells/mm(3) in 2008. Further, 2013 guidelines raised the threshold for initiation to ≤500 cells/mm(3) and suggest immediate therapy for key affected populations. In 2015, guidelines recommend offering immediate treatment to all patients. By reviewing the history of HIV and the scale-up of treatment delivery in Rwanda since the genocide, this paper highlights some of the key innovations of the Government of Rwanda and demonstrates the ways in which the national response to the HIV epidemic has catalyzed the implementation of interventions that have helped strengthen the overall health system.

Indexed as

Anti-Retroviral AgentsDeveloping CountriesHIV InfectionsHumansMaleRwandaAnti-Retroviral Agents

Identifiers

PMID26354601
PMCPMC4564958

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.