Evidence map›Paper›PMID 26354106›Full record

ArticleSleep & breathing = Schlaf & Atmung2016

Association between sleep quality and inflammatory complement components in collegiate males.

Md Dilshad Manzar, Mohammad Muntafa Rajput, Wassilatul Zannat, Unaise Abdul Hameed, Muhammed Deeb Al-Jarrah, David Warren Spence, Seithikurippu R Pandi-Perumal, Ahmed S BaHammam, M Ejaz Hussain

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Md Dilshad ManzarCentre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia, Maulana Mohammad Ali Jauhar Marg, New Delhi, 110025, India.
Mohammad Muntafa RajputDepartment of Biochemistry, Institute of Home Economics, University of Delhi, New Delhi, India.
Wassilatul ZannatCentre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia, Maulana Mohammad Ali Jauhar Marg, New Delhi, 110025, India.
Unaise Abdul HameedDepartment of Physiotherapy, Fatima College of Health Sciences, Al Mafraq, Abu Dhabi City, United Arab Emirates.
Muhammed Deeb Al-JarrahDepartment of Physiotherapy, Fatima College of Health Sciences, Al Mafraq, Abu Dhabi City, United Arab Emirates.
David Warren Spence, 652 Dufferin St., Toronto, ON, Canada.
Seithikurippu R Pandi-PerumalSomnogen Canada Inc, Toronto, ON, Canada.
Ahmed S BaHammamDepartment of Medicine, College of Medicine, The University Sleep Disorders Centre, Riyadh, Saudi Arabia.
M Ejaz HussainCentre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia, Maulana Mohammad Ali Jauhar Marg, New Delhi, 110025, India. hussainmejaz@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn accumulating amount of evidence has linked humoral mediators of inflammation with sleep measures. Nevertheless, important details of this association, in particular the role of the complement components in the context of chronic sleep attributes, have remained largely uncharacterized. MATERIALS AND

methodsFifty university students (age, 23.3 ± 3.8 years; BMI, 23.7 ± 2.9 kg/m(2)) completed the study. Four dichotomized sleep measures assessed by the Pittsburgh Sleep Quality Index (PSQI) were used in association analysis using binary logistic regression with complement component 3, 4, and complement factor I (CFI). The sleep measures were defined as sleep quality (good sleep/poor sleep; PSQI ≤5/PSQI >5), bedtime (early/late; before 00:00 h/after 0:00 h), sleep duration (short/normal ≤6 h/>6 h), and sleep onset latency (normal/disturbed; 0-1 score/2-3 score on the PSQI component of sleep latency).

resultsThe complement component 4 was associated with sleep quality (unadjusted, OR = 1.025, p < 0.05; adjusted for age, OR = 1.025, p < 0.05; adjusted for BMI, OR = 1.027, p < 0.05) and sleep duration (unadjusted, OR = 1.041, p < 0.01; adjusted for age, OR = 1.041, p < 0.01; adjusted for BMI, OR = 1.046, p < 0.01). CFI was associated with bedtime (unadjusted, OR = 0.737, p < 0.01; adjusted for age, OR = 0.717, p < 0.01; adjusted for BMI, OR = 0.677, p < 0.01) and with sleep duration (unadjusted, OR = 0.796, p < 0.05; adjusted for age, OR = 0.796, p < 0.05).

conclusionThe findings indicate the importance of the role of complement components in the dynamics of sleep. Therefore, sleep should be assessed in conditions where complement components are affected.

Indexed as

Body Mass IndexComplement C4HumansInflammationMaleReference ValuesSleepSleep Wake DisordersYoung AdultComplement C4Complement componentInflammationPittsburgh Sleep Quality IndexSleepSleep durationSleep quality

Identifiers

PMID26354106

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.