Evidence map›Paper›PMID 26353943›Full record

ReviewCurrent genetics2016

Last hope for the doomed? Thoughts on the importance of a parasexual cycle for the yeast Candida albicans.

Jan Schmid, Paul T Magee, Barbara R Holland, Ningxin Zhang, Richard D Cannon, Beatrice B Magee

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Parasexuality ofFrontiers in cellular and infection microbiology · 2021
    Review
  4. Article
  5. Review
  6. Biological Roles of Protein-Coding Tandem Repeats in the YeastJournal of fungi (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jan SchmidInstitute of Fundamental Sciences, College of Sciences, Massey University, Science Tower D, Riddet Road, Palmerston North, 4410, New Zealand. j.schmid@massey.ac.nz.ORCID http://orcid.org/0000-0001-8794-4175
Paul T MageeDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN, 55455, USA.
Barbara R HollandSchool of Physical Sciences, University of Tasmania, Hobart, 7001, Australia.
Ningxin ZhangInstitute of Fundamental Sciences, College of Sciences, Massey University, Science Tower D, Riddet Road, Palmerston North, 4410, New Zealand.
Richard D CannonDepartment of Oral Sciences, University of Otago, Dunedin, 9054, New Zealand.
Beatrice B MageeDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN, 55455, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The yeast Candida albicans, a commensal colonizer and occasional pathogen of humans, has a rudimentary mating ability. However, mating is a cumbersome process that has never been observed outside the laboratory, and the population structure of the species is predominantly clonal. Here we discuss recent findings that indicate that mating ability is under selection in C. albicans, i.e. that it is a biologically relevant process. C. albicans strains can only mate after they have sustained genetic damage. We propose that the rescue of such damaged strains by mating may be the primary reason why mating ability is under selection.

Indexed as

Candida albicansGenes, Mating Type, FungalSelection, GeneticCandida albicansClonalityEvolutionMatingParasexual cycle

Identifiers

PMID26353943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.