Evidence map›Paper›PMID 26353936›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2015

Recent Advances on the Total Syntheses of Communesin Alkaloids and Perophoramidine.

Barry M Trost, Maksim Osipov

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Unified Total Synthesis ofJournal of the American Chemical Society · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Natural product anticipation through synthesis.Nature reviews. Chemistry · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Barry M TrostDepartment of Chemistry, Stanford University, 333 Campus Drive, Stanford, CA 94305-5080 (USA). bmtrost@stanford.edu.
Maksim OsipovDepartment of Chemistry, Stanford University, 333 Campus Drive, Stanford, CA 94305-5080 (USA).

Funding

NOVEL SYNTHETIC APPROACHES TO ANTITUMOR COMPOUNDSR01GM033049 · NIGMS · UNIVERSITY OF WISCONSIN MADISON · PI TROST, BARRY M · 1985 to 2016
$6.5M
NIGMS NIH HHS GM033049NIGMS NIH HHS R01 GM033049
6 · The paper itself

Abstract

The communesin alkaloids are a diverse family of Penicillium-derived alkaloids. Their caged-polycyclic structure and intriguing biological profiles have made these natural products attractive targets for total synthesis. Similarly, the ascidian-derived alkaloid, perophoramidine, is structurally related to the communesins and has also become a popular target for total synthesis. This review serves to summarize the many elegant approaches that have been developed to access the communesin alkaloids and perophoramidine. Likewise, strategies to access the communesin ring system are reviewed.

Indexed as

AlkaloidsAnimalsBiological ProductsHeterocyclic Compounds, 4 or More RingsHydrocarbons, HalogenatedMolecular StructureStereoisomerismUrochordataAlkaloidsBiological Productscommunesin AHeterocyclic Compounds, 4 or More RingsHydrocarbons, Halogenatedperophoramidinealkaloidscommunesinperophoramidinetotal synthesisvicinal quaternary stereocenters

Identifiers

PMID26353936
PMCPMC4698125

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.