ArticleGenome biology2015
Small-scale gene duplications played a major role in the recent evolution of wheat chromosome 3B.
Article in Genome biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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47 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Genome-wide analysis, expansion and expression of the NAC family under drought and heat stresses in bread wheat (T. aestivum L.).PloS one · 2019Pooled it
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- Dissecting the genetic architecture of pre-harvest sprouting tolerance in Indian dwarf wheat (Triticum sphaerococcum) by multi-locus association analysis.Scientific reports · 2025Article
- Dualistic MADS-box evolution forged legume diversity post-WGD.Frontiers in plant science · 2025Article
- Exploring the genetic diversity and population structure of an ancient hexaploid wheat species Triticum sphaerococcum using SNP markers.BMC plant biology · 2024Article
- Genome-Wide Analysis ofPlants (Basel, Switzerland) · 2024Article
- Genomic insights into the chromosomal elongation in a family of Collembola.Proceedings. Biological sciences · 2024Article
- Contribution of Duplicated Nucleotide-Binding Leucine-Rich Repeat (NLR) Genes to Wheat Disease Resistance.Plants (Basel, Switzerland) · 2023Review
- The evolutionary patterns, expression profiles, and genetic diversity of expanded genes in barley.Frontiers in plant science · 2023Article
- Location and Identification on Chromosome 3B of Bread Wheat of Genes Affecting Chiasma Number.Plants (Basel, Switzerland) · 2022Article
- Identification of ankyrin-transmembrane-type subfamily genes in Triticeae species revealsFrontiers in plant science · 2022Article
- Homoeolog Inference Methods Requiring Bidirectional Best Hits or Synteny Miss Many Pairs.Genome biology and evolution · 2021Article
- Genome-wide identification and phylogenetic relationships of the3 Biotech · 2021Article
- Extensive structural variation in the Bowman-Birk inhibitor family in common wheat (Triticum aestivum L.).BMC genomics · 2021Article
- The Landscape of the Genomic Distribution and the Expression of the F-Box Genes Unveil Genome Plasticity in Hexaploid Wheat during Grain Development and in Response to Heat and Drought Stress.International journal of molecular sciences · 2021Article
- New insights into homoeologous copy number variations in the hexaploid wheat genome.The plant genome · 2021Article
- Evaluation of genetic structure in European wheat cultivars and advanced breeding lines using high-density genotyping-by-sequencing approach.BMC genomics · 2021Article
- Genome-Wide Diversity of MADS-Box Genes in Bread Wheat is Associated with its Rapid Global Adaptability.Frontiers in genetics · 2021Article
- Comparative Analysis of the Glutathione S-Transferase Gene Family of FourInternational journal of genomics · 2021Article
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Authors and funding
7 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBread wheat is not only an important crop, but its large (17 Gb), highly repetitive, and hexaploid genome makes it a good model to study the organization and evolution of complex genomes. Recently, we produced a high quality reference sequence of wheat chromosome 3B (774 Mb), which provides an excellent opportunity to study the evolutionary dynamics of a large and polyploid genome, specifically the impact of single gene duplications.
resultsWe find that 27 % of the 3B predicted genes are non-syntenic with the orthologous chromosomes of Brachypodium distachyon, Oryza sativa, and Sorghum bicolor, whereas, by applying the same criteria, non-syntenic genes represent on average only 10 % of the predicted genes in these three model grasses. These non-syntenic genes on 3B have high sequence similarity to at least one other gene in the wheat genome, indicating that hexaploid wheat has undergone massive small-scale interchromosomal gene duplications compared to other grasses. Insertions of non-syntenic genes occurred at a similar rate along the chromosome, but these genes tend to be retained at a higher frequency in the distal, recombinogenic regions. The ratio of non-synonymous to synonymous substitution rates showed a more relaxed selection pressure for non-syntenic genes compared to syntenic genes, and gene ontology analysis indicated that non-syntenic genes may be enriched in functions involved in disease resistance.
conclusionOur results highlight the major impact of single gene duplications on the wheat gene complement and confirm the accelerated evolution of the Triticeae lineage among grasses.
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