Evidence map›Paper›PMID 26352665›Full record

ArticleCell reports2015

In the Right Place at the Right Time: Is TMC1/2 the Transduction Channel for Hearing?

Artur A Indzhykulian, David P Corey

Open access · goldAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Artur A IndzhykulianDepartment of Neurobiology and Howard Hughes Medical Institute, Harvard Medical School, Harvard University, 220 Longwood Avenue, Boston, MA 02115. Electronic address: artur_indzhykulian@hms.harvard.edu.
David P CoreyDepartment of Neurobiology and Howard Hughes Medical Institute, Harvard Medical School, Harvard University, 220 Longwood Avenue, Boston, MA 02115. Electronic address: dcorey@hms.harvard.edu.
Harvard University · USHoward Hughes Medical Institute · US

Funding

MOLECULAR MECHANISMS OF AUDITORY TRANSDUCTIONR01DC000304 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI DAVID P COREY, Marcos Sotomayor · 1989 to 2026
$9.3M
Howard Hughes Medical Institute
6 · The paper itself

Abstract

Recent papers suggest that TMC1 and TMC2 constitute the ion channels mediating hearing and balance. Kurima et al. (2015) now show these proteins are expressed in the right place and at the right time, bringing us closer to definitive identification.

Indexed as

AnimalsCiliaFemaleHair Cells, Auditory, InnerMaleMembrane ProteinsMembrane Proteins

Identifiers

PMID26352665
OpenAlexW1848046942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.