ArticleEpidemiology (Cambridge, Mass.)2015
Ambient Ammonia Exposures in an Agricultural Community and Pediatric Asthma Morbidity.
Article in Epidemiology (Cambridge, Mass.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Association of distance to swine concentrated animal feeding operations with immune-mediated diseases: An exploratory gene-environment study.Environment international · 2023Pooled it
- Randomized trial of a portable HEPA air cleaner intervention to reduce asthma morbidity among Latino children in an agricultural community.Environmental health : a global access science source · 2022Trial
- Trial
- Effectiveness of portable HEPA air cleaners on reducing indoor PMIndoor air · 2021Trial
- A Spatiotemporal Modeling Approach for Predicting Concentrations of Ammonia in an Agricultural Region.GeoHealth · 2026Article
- Air pollution from livestock farms and lung function decline in neighboring residents over 7 years.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Barriers and Facilitators to Early-life Wildfire Smoke Protection in a Rural Population: The Role of Community in Research and Public Health Practice.Research square · 2025Article
- Nasopharyngeal microbiota is influenced by agricultural air pollution in individuals with and without COPD.Scientific reports · 2025Article
- Influence ofAnimals : an open access journal from MDPI · 2025Article
- Respiratory and allergic health effects in children living near agriculture: A review.The Science of the total environment · 2022Review
- Airborne chemical pollution and children's asthma incidence rate in Minsk.Journal of preventive medicine and hygiene · 2021Article
- Geospatial Correlation Analysis between Air Pollution Indicators and Estimated Speed of COVID-19 Diffusion in the Lombardy Region (Italy).International journal of environmental research and public health · 2021Article
- The home air in agriculture pediatric intervention (HAPI) trial: Rationale and methods.Contemporary clinical trials · 2020Article
- Estimated time-varying exposures to air emissions from animal feeding operations and childhood asthma.International journal of hygiene and environmental health · 2020Article
- Association of Organophosphate Pesticide Exposure and a Marker of Asthma Morbidity in an Agricultural Community.Journal of agromedicine · 2020Article
- Effects of Low-level Occupational Exposure to Ammonia on Hematological Parameters and Kidney Function.The international journal of occupational and environmental medicine · 2019Article
- Impacts of Intensive Livestock Production on Human Health in Densely Populated Regions.GeoHealth · 2017Article
- Rural Asthma: Current Understanding of Prevalence, Patterns, and Interventions for Children and Adolescents.Current allergy and asthma reports · 2017Review
- Proximity to Industrial Food Animal Production and Asthma Exacerbations in Pennsylvania, 2005-2012.International journal of environmental research and public health · 2017Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
backgroundLarge-scale animal feeding operations compromise regional air quality in the rural US through emission of pollutants, such as ammonia gas. Exposure to airborne pollution from animal feeding operations may cause pediatric asthma exacerbations in surrounding communities.
objectivesTo describe spatial and temporal patterns in ambient ammonia concentrations in an agricultural region, and to investigate associations between short-term fluctuations in ammonia and subsequent changes in respiratory health in children with asthma.
methodsFor 13 months in the Yakima Valley of Washington State, 14 monitors sampled ammonia in outdoor air for 24-hour periods every 6 days. School-age children with asthma (n = 51) were followed for two health outcomes: biweekly reports of asthma symptoms and quick relief medication usage, and daily measurements of forced expiratory volume in 1 second. We assessed associations between each outcome and ammonia using generalized estimating equations.
resultsTwenty-four-hour ammonia concentrations varied from 0.2 to 238.1 μg/m during the study period and displayed a strong correlation with proximity to animal feeding operations. The percentage of forced expiratory volume in 1 second was 3.8% lower (95% confidence interval = 0.2, 7.3) per interquartile increase in 1-day lagged ammonia concentration and 3.0% lower (95% confidence interval = 0.5, 5.8) for 2-day lagged concentration. We observed no associations between self-reported asthma symptoms or medication usage and estimated ammonia exposure.
conclusionsAmmonia concentrations were elevated in this community and strongly predicted by proximity to animal feeding operations. Ammonia's association with acute lung function decrements in children with asthma in the surrounding community may be causal or, alternatively, ammonia may be a marker for other pollutants from animal feeding operations associated with respiratory effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.