Evidence map›Paper›PMID 26351529›Full record

SynthesisJournal of medicine and life

Features of Polycystic Ovary Syndrome in adolescence.

P Tsikouras, L Spyros, B Manav, S Zervoudis, C Poiana, T Nikolaos, P Petros, M Dimitraki, C Koukouli, G Galazios and 1 more

Open access · greenAbstract readSystematic Review
PubMed Full text at PMC
In one paragraph

Synthesis in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
7.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Association ofDisease markers · 2020
    Article
  9. Polycystic ovary syndrome throughout a woman's life.Journal of assisted reproduction and genetics · 2018
    Review
  10. Polycystic Ovary Syndrome (PCOS), Diagnostic Criteria, and AMHAsian Pacific journal of cancer prevention : APJCP · 2017
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

P TsikourasDepartment of Obstetrics and Gynaecology, Democritus University of Thrace, Greece.
L SpyrosDepartment of Obstetrics and Gynaecology, Democritus University of Thrace, Greece.
B ManavDepartment of Obstetrics and Gynaecology, Democritus University of Thrace, Greece.
S ZervoudisDepartment of Obstetrics/Gynaecology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania; Rea Hospital Athens, Greece.
C PoianaDepartment of Endocrinology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
T NikolaosDepartment of Obstetrics and Gynaecology, Democritus University of Thrace, Greece.
P PetrosDepartment of Obstetrics and Gynaecology, Democritus University of Thrace, Greece.
M DimitrakiDepartment of Obstetrics and Gynaecology, Democritus University of Thrace, Greece.
C KoukouliDepartment of Obstetrics and Gynaecology, Democritus University of Thrace, Greece.
G GalaziosDepartment of Obstetrics and Gynaecology, Democritus University of Thrace, Greece.
G F von TempelhoffDepartment of Obstetrics and Gynaecology, Clinicum Aschaffenburg, Teaching Hospital University of Würzburg, Germany.
Carol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleTo elucidate the prepubertal risk factors associated with the development of Polycystic Ovary Syndrome (PCOS) and determine the special clinical manifestations of the syndrome in this transitional time of a woman's life.

objectiveTo propose therapeutic targets and regimens, not only to prevent the long-term complications of the syndrome, but also to improve the self-esteem of a young girl who matures into womanhood. METHODS AND

resultsA systematic review of literature was performed through electronic database searches (Pubmed, Medline and Embase). Studies published in English-language, peer-reviewed journals from 1996 to 2013 were included. The selected studies focused on the risk factors, the unique features and treatment options of the PCOS in puberty. The pathogenesis of the PCOS was hypothesized to be based on interactions between genetic and certain environmental factors. The diagnosis was usually difficult in young girls. The syndrome was related to a greater risk of future infertility, type II diabetes mellitus, the metabolic syndrome and cardiovascular disease. Early treatment was crucial to prevent the long-term complications of the syndrome, especially infertility and cardiovascular disease. DISCUSSION: The recognition of the early signs of PCOS during or even before adolescence is of great importance. It is essential to establish the correct diagnosis for PCOS and rule out other causes of androgen excess in young women with hyperandrogenism. The type of treatment applied should be considered on an individual basis. ABBREVIATIONS: PCOS = Polycystic Ovary Syndrome.

Indexed as

AdolescentDiagnosis, DifferentialDiagnostic ImagingFemaleHumansPolycystic Ovary SyndromePubertyRisk FactorsadolescenceanovulationhyperandrogenismPolycystic Ovary Syndromepuberty

Identifiers

PMID26351529
PMCPMC4556908
OpenAlexW1646975093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.