Evidence map›Paper›PMID 26351528›Full record

ReviewJournal of medicine and life

Quantification of liver fibrosis in chronic hepatitis B virus infection.

C F Jieanu, B S Ungureanu, D L Săndulescu, I A Gheonea, D R Tudorașcu, M E Ciurea, V L Purcărea

Abstract readReview
In one paragraph

Review in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Radiology-pathology correlation in staging of liver fibrosis using superb microvascular imaging.Diagnostic and interventional radiology (Ankara, Turkey) · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C F JieanuResearch Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania.
B S UngureanuResearch Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania.
D L SăndulescuResearch Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania.
I A GheoneaResearch Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania.
D R TudorașcuResearch Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania.
M E CiureaResearch Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania.
V L Purcărea"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic hepatitis B virus infection (HBV) is considered a global public issue with more than 78.000 people per year dying of its evolution. With liver transplantation as the only viable therapeutic option but only in end-stage disease, hepatitis B progression may generally be influenced by various factors. Assessing fibrosis stage plays an important part in future decisions on the patients' wealth with available antiviral agents capable of preventing fibrosis passing to an end-stage liver disease. Several methods have been taken into consideration as an alternative for HBV quantification status, such as imaging techniques and serum based biomarkers. Magnetic resonance imaging, ultrasound, and elastography are considered non-invasive imaging techniques frequently used to quantify disease progression as well as patients future prognostic. Consequently, both direct and indirect biomarkers have been studied for differentiating between fibrosis stages. This paper reviews the current standings in HBV non-invasive liver fibrosis quantification, presenting the prognostic factors and available assessment procedures that might eventually replace liver biopsy.

Indexed as

BiomarkersElasticity Imaging TechniquesHepatitis B, ChronicHepatitis B virusHumansLiver CirrhosisBiomarkersend-stage liver diseasefibrosisHBVnon-invasive methods

Identifiers

PMID26351528
PMCPMC4556907

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.