ArticleEvidence-based complementary and alternative medicine : eCAM2015
Antiatherogenic and Cardioprotective Effects of Black Chokeberry (Aronia melanocarpa) Juice in Aging Rats.
Article in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects ofThe review of diabetic studies : RDS · 2022Pooled it
- Standardized Aronia melanocarpa extract regulates redox status in patients receiving hemodialysis with anemia.Molecular and cellular biochemistry · 2021Trial
- Influence of Hydrothermal and Chemical Modifications of Potato Starch on Its Performance as a Carrier Matrix for Selected Polyphenolic Compound Derived from Chokeberry (Molecules (Basel, Switzerland) · 2026Article
- Green Extraction of Phenolic Compounds fromAntioxidants (Basel, Switzerland) · 2024Article
- Biogenic Synthesis of Silver Nanoparticles Mediated byLife (Basel, Switzerland) · 2024Article
- Functional Activities and Mechanisms ofCurrent issues in molecular biology · 2024Review
- Review
- Health Benefits of Antioxidant Bioactive Compounds in the Fruits and Leaves ofAntioxidants (Basel, Switzerland) · 2023Review
- Microbiota-Derived Natural Products Targeting Cancer Stem Cells: Inside the Gut Pharma Factory.International journal of molecular sciences · 2023Review
- Chokeberry (Nutrients · 2022Review
- Black Chokeberry (Foods (Basel, Switzerland) · 2021Article
- Review
- The Efficacy of Black Chokeberry Fruits against Cardiovascular Diseases.International journal of molecular sciences · 2021Review
- Bioactive Compounds from Germinated Brown Rice Protect Cardiomyocytes Against Simulated Ischemic/Reperfusion Injury by Ameliorating Mitochondrial Dysfunction.Drug design, development and therapy · 2021Article
- Assessment of Hepatoprotective Effect of Chokeberry Juice in Rats Treated Chronically with Carbon Tetrachloride.Molecules (Basel, Switzerland) · 2020Article
- Honey and Its Phenolic Compounds as an Effective Natural Medicine for Cardiovascular Diseases in Humans?Nutrients · 2020Review
- Effects of different dietary regimes alone or in combination with standardized Aronia melanocarpa extract supplementation on lipid and fatty acids profiles in rats.Molecular and cellular biochemistry · 2019Article
- Black ChokeberryMolecules (Basel, Switzerland) · 2019Review
- StandardizedInternational journal of molecular sciences · 2018Article
- Dietary Supplements with Antiplatelet Activity: A Solution for Everyone?Advances in nutrition (Bethesda, Md.) · 2018Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Age-related diseases are a social problem of global significance and their prevention by natural products is a research area of particular interest. The present study is an approach to counteract the risk factors for atherosclerosis arising in the aging process by supplementation of chokeberry juice. It employed a model of healthy adult rats monitored for a number of somatometric, serum lipidogram, and histopathological parameters, related to risk factors and their response to supplementation with antioxidant-rich chokeberry juice. The results were used to calculate different atherogenic and cardioprotective indices, and all results were compared to those of young healthy rats. Chokeberry juice proved an extremely rich source of polyphenols resulting in very high antioxidant activity. Treatment with Aronia juice significantly lowered the proatherogenic low-density lipoprotein fraction of the animals studied and led to a 16.5% decrease in their total cholesterol. Atherogenic indices in Aronia-supplemented animals clearly showed lower atherogenic risk and cardioprotective indices indicated protection of the cardiovascular system. Besides that, chokeberry juice retarded the age-related changes in the aortic wall and can be recommended as a prophylactic tool for healthy aging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.