Evidence map›Paper›PMID 26351508›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2015

Allium sativum L. Improves Visual Memory and Attention in Healthy Human Volunteers.

Sara Tasnim, Parsa Sanjana Haque, Md Sazzadul Bari, Md Monir Hossain, Sardar Mohd Ashraful Islam, Mohammad Shahriar, Mohiuddin Ahmed Bhuiyan, Muhammad Shahdaat Bin Sayeed

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Review
  3. An InJournal of pharmacopuncture · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sara TasnimDepartment of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Parsa Sanjana HaqueDepartment of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Md Sazzadul BariDepartment of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Md Monir HossainDepartment of Pharmacy, Noakhali Science and Technology University, Noakhali 3814, Bangladesh.
Sardar Mohd Ashraful IslamDepartment of Pharmacy, University of Asia Pacific, Dhaka 1209, Bangladesh.
Mohammad ShahriarDepartment of Pharmacy, University of Asia Pacific, Dhaka 1209, Bangladesh.
Mohiuddin Ahmed BhuiyanDepartment of Pharmacy, University of Asia Pacific, Dhaka 1209, Bangladesh.
Muhammad Shahdaat Bin SayeedDepartment of Pharmacy, University of Asia Pacific, Dhaka 1209, Bangladesh ; Department of Clinical Pharmacy and Pharmacology, University of Dhaka, Dhaka 1000, Bangladesh.
University of Dhaka · BDUniversity of Asia Pacific · BDNoakhali Science and Technology University · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have shown that Allium sativum L. (AS) protects amyloid-beta peptide-induced apoptosis, prevents oxidative insults to neurons and synapses, and thus prevent Alzheimer's disease progression in experimental animals. However, there is no experimental evidence in human regarding its putative role in memory and cognition. We have studied the effect of AS consumption by healthy human volunteers on visual memory, verbal memory, attention, and executive function in comparison to control subjects taking placebo. The study was conducted over five weeks and twenty volunteers of both genders were recruited and divided randomly into two groups: A (AS) and B (placebo). Both groups participated in the 6 computerized neuropsychological tests of the Cambridge Neuropsychological Test Automated Battery (CANTAB) twice: at the beginning and after five weeks of the study. We found statistically significant difference (p < 0.05) in several parameters of visual memory and attention due to AS ingestion. We also found statistically nonsignificant (p > 0.05) beneficial effects on verbal memory and executive function within a short period of time among the volunteers. Study for a longer period of time with patients suffering from neurodegenerative diseases might yield more relevant results regarding the potential therapeutic role of AS.

Identifiers

PMID26351508
PMCPMC4550798
OpenAlexW1772512728

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.