Evidence map›Paper›PMID 26351484›Full record

ArticleIranian journal of pathology2015

Frequency of Human Papillomavirus Genotypes 6, 11, 16, 18 And 31 in Paraffin-Embedded Tissue Samples of Invasive Breast Carcinoma, North- East of Iran.

Masoumeh Salehpour, Naser Tayyebi Meibodi, Roghayeh Teimourpour, Adel Ghorani-Azam, Samaneh Sepahi, Sina Rostami, Zahra Meshkat

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Absence ofIranian journal of pathology · 2019
    Article
  8. Human papillomavirus and breast cancer in Iran: a meta- analysis.Iranian journal of basic medical sciences · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Masoumeh SalehpourAntimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Naser Tayyebi MeibodiSkin Diseases and Cutaneous Leishmanaisis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Roghayeh TeimourpourAntimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Adel Ghorani-AzamDept. of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
Samaneh SepahiDept. of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
Sina RostamiDept. of Biology, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
Zahra MeshkatAntimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IRFerdowsi University of Mashhad · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

objectiveBreast cancer is the most common female malignancy. Detection of DNA of human papillomaviruses (HPVs) in breast carcinomas suggests that the virus may play a role in the pathogenesis of this disease. The aim of this study was to evaluate the frequency of HPVs genotypes 6, 11, 16, 18 and 31 in paraffin-embedded tissue samples of invasive breast carcinomas.

methodsThree hundred and twenty six paraffin-embedded tissue samples of breast cancer were studied. PCR was performed using specific primers for HPV genotypes.

resultsOf total 206 (63.2%) samples positive for Beta-globin gene, 54 (26.2%) were HPV-positive and 152 (73.8%) were negative for HPV. Distribution of HPV genotypes were as follows: 19 (25.7%) were positive for genotype 11, 5 (6.8%) were positive for genotype 6; and 2 cases (2.7%) were positive for both genotypes 6 and 11. Samples were also screened for HPV genotypes 16, 18 and 31 but none was positive.

conclusionThe current study confirmed the association of HPV and breast cancer. However, all samples were negative for high-risk HPV types 16, 18 and 31.

Indexed as

Breast CancerHuman Papillomavirus (HPV)Polymerase Chain Reaction (PCR)

Identifiers

PMID26351484
PMCPMC4539770
OpenAlexW1855522668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.