Evidence map›Paper›PMID 26351250›Full record

ArticleJournal of neurogastroenterology and motility2015

Temporary Endoscopic Stimulation in Gastroparesis-like Syndrome.

Sanjeev Singh, Jeff McCrary, Archana Kedar, Stephen Weeks, Brian Beauerle, Andrew Weeks, Omer Endashaw, Chris Lahr, Warren Starkebaum, Thomas Abell

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurogastroenterology and motility, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Nausea and Vomiting in 2021: A Comprehensive Update.Journal of clinical gastroenterology · 2021
    Review
  4. The Surgeon's Role in Gastric Electrical Stimulation Therapy for Gastroparesis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Expanding Indications of Gastric Electrical Stimulation.Journal of neurogastroenterology and motility · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sanjeev SinghDepartment of General Internal Medicine, Palliative Medicine and Medical Education, Department of Medicine, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Jeff McCraryDivision of Gastroenterology, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Archana KedarDivision of Gastroenterology, Hepatology & Nutrition, Department of Medicine, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Stephen WeeksDivision of Gastroenterology, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Brian BeauerleDivision of Gastroenterology, Hepatology & Nutrition, Department of Medicine, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Andrew WeeksDivision of Gastroenterology, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Omer EndashawDivision of Gastroenterology, Hepatology & Nutrition, Department of Medicine, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Chris LahrDepartment of Surgery, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Warren StarkebaumStarkebaum and Associates, Plymouth, Minnesota, USA.
Thomas AbellDepartment of General Internal Medicine, Palliative Medicine and Medical Education, Department of Medicine, University of Louisville School of Medicine, Louisville, Kentucky, USA.ORCID http://orcid.org/0000-0002-3175-5161
University of Louisville · USUniversity of Mississippi Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsGastroparesis-like syndrome (GLS) is defined as gastroparesis-like symptoms with normal gastric scintigraphy. While the efficacy of gastric electrical stimulation (GES) in gastroparesis is well known, the utility of GES in GLS is largely unknown. Our aim was to clarify the role of GES in GLS. We implanted consecutive patients with symptoms of gastroparesis with temporary gastric electrical stimulation and observed changes in gastric scintigraphy and total symptom score.

methodsFive hundred and fifty-one patients suffering from symptoms of gastroparesis (nausea, vomiting, bloating/distension, anorexia/early satiety, and abdominal pain) with negative endoscopy underwent gastric scintigraphy with analysis of 1) solid radionuclide gastric emptying at 1, 2, and 4 hours (% remaining); 2) area under the gastric emptying curve (AUC) at 1, 2, and 4 hours; and 3) total gastric emptying test (GET) (the sum of 1, 2, and 4 hour values). Patients were stratified into: delayed gastric emptying, normal gastric emptying, and rapid gastric emptying (Appendix). Of the 551 patients in the larger cohort, 379 had implantation of temporary gastric electrical stimulation (tGES). Gastrointestinal symptoms and gastric emptying were com - pared pre and post tGES implantation.

resultsAfter tGES, 2 hour gastric retention decreased (P < 0.01) for the delayed patients, and increased (P < 0.001) for normal and rapid patients. These changes were accompanied by improvements (P < 0.001) in vomiting, nausea, and total symptom scores in all 3 subgroups.

conclusionsGastric electrical stimulation may be an effective therapy for treating the symptoms of gastroparesis with normal gastric emptying. Further exploration of endoscopic electrical stimulation as a treatment for gastroparesis-like symptoms with non-delayed gastric emptying is needed.

Indexed as

Abdominal painElectrical stimulationGastroparesisNauseaVomiting

Identifiers

PMID26351250
PMCPMC4622134
OpenAlexW2319449468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.