SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2015
A systematic review of neuropsychological outcomes following posterior fossa tumor surgery in children.
Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Quality of life in survivors of pediatric medulloblastoma: a systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Pooled it
- Trial
- Language Processing in Posterior Fossa Tumour Patients: Psycholinguistic Insights into the Word-Finding Ability.Cerebellum (London, England) · 2026Article
- Subcortical alterations following pediatric posterior fossa brain tumor treatment: A longitudinal MRI study.Neuroimage. Reports · 2025Article
- Long-term neurocognitive sequelae in pediatric medulloblastoma survivors treated according to the HIT protocol.Journal of neuro-oncology · 2025Article
- Visual-Motor Functions and Associated Cognitive Outcomes in Pediatric Cancer Survivors.Medical sciences (Basel, Switzerland) · 2025Article
- Review
- Prospective analysis on possible changes of cognitive functions in children on follow-up for brain tumor.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Effects of cognitive-motor intervention for pediatric posterior fossa tumor survivors: results of a pilot study.Journal of neuro-oncology · 2024Article
- Late effects of medulloblastoma treatment: multidisciplinary approach of survivors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Goal-directed therapeutic exercise for paediatric posterior fossa brain tumour survivors: a qualitative analysis of experiences.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Picture naming test through the prism of cognitive neuroscience and linguistics: adapting the test for cerebellar tumor survivors-or pouring new wine in old sacks?Frontiers in psychology · 2024Review
- A single-center experience of central nervous system tumors in children under three years old.Frontiers in pediatrics · 2024Article
- Executive and social functioning in pediatric posterior fossa tumor survivors and healthy controls.Neuro-oncology practice · 2023Article
- Comparison of Neurocognitive Functioning and Fine Motor Skills in Pediatric Cancer Survivors and Healthy Children.Cancers · 2022Article
- Motor Functioning and Intelligence Quotient in Paediatric Survivors of a Fossa Posterior Tumor Following a Multidisciplinary Rehabilitation Program.International journal of environmental research and public health · 2022Article
- A prospective behavioral and imaging study exploring the impact on long-term memory of radiotherapy delivered for a brain tumor in childhood and adolescence.Clinical and translational radiation oncology · 2022Article
- Comparison of neuropsychological functioning in pediatric posterior fossa tumor survivors: Medulloblastoma, low-grade astrocytoma, and healthy controls.Pediatric blood & cancer · 2022Article
- Impact of COVID-19 on adolescent and emerging adult brain tumor survivors and their parents.Pediatric blood & cancer · 2021Article
- A Diagnostic Algorithm for Posterior Fossa Tumors in Children: A Validation Study.AJNR. American journal of neuroradiology · 2021Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCentral nervous system tumors are the most common solid tumors in the pediatric population. As children with central nervous system (CNS) tumors are surviving into adolescence and adulthood, more research is being focused on the long-term cognitive outcomes of the survivors. This review examines the literature on different cognitive outcomes of survivors of different childhood posterior fossa CNS tumor types.
methodsThe authors reviewed the literature for articles published from 2000 to 2012 about long-term neuropsychological outcomes of children diagnosed with posterior fossa brain tumors before the age of 18, which distinguished between histological tumor types, and had a minimum follow-up of 3 years.
resultsThe literature search returned 13 articles, and a descriptive analysis was performed comparing intelligence quotient (IQ), attention/executive function, and memory components of 456 survivors of childhood posterior fossa tumors. Four articles directly compared astrocytoma and medulloblastoma survivors and showed medulloblastoma survivors fared worse in IQ, attention/executive function, and memory measurements. Five articles reporting medulloblastomas found IQ, attention, and memory scores to be significantly below the standardized means. Articles examining astrocytoma survivors found IQ scores within the normal range for the population. Survivors of ependymomas reported 2/23 survivors impaired on IQ scores, while a second study reported a significant number of ependymoma survivors lower than the expected population norm.
conclusionsTumor histopathology and the type of postoperative adjuvant therapy seem to have a significant impact on the long-term neuropsychological complications of pediatric posterior fossa CNS tumor survivors. Age at diagnosis and treatment factors are important variables that affect the outcomes of the survivors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.