Evidence map›Paper›PMID 26351221›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2015

Pediatric cerebellar astrocytoma: a review.

Christopher M Bonfield, Paul Steinbok

Abstract readReview
PubMed Publisher
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Pilocytic astrocytoma: A rare case report.Radiology case reports · 2025
    Article
  3. Review
  4. Pediatric hemispheric cerebellar low-grade gliomas: clinical approach, diagnosis, and management challenges-experience at a tertiary care children's hospital.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Observational
  5. Article
  6. Review
  7. Article
  8. Review
  9. Mapping of long-term cognitive and motor deficits in pediatric cerebellar brain tumor survivors into a cerebellar white matter atlas.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  10. Ataxia and mobility in children following surgical resection of posterior fossa tumour: A longitudinal cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  11. Review
  12. Article
  13. Posterior Fossa Society Consensus Meeting 2018: a synopsis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
    Article
  14. Review
  15. Review
  16. Article
  17. Preoperative neurocognitive evaluation as a predictor of brain tumor grading in pediatric patients with supratentorial hemispheric tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016
    Article
  18. Consensus paper on post-operative pediatric cerebellar mutism syndrome: the Iceland Delphi results.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher M BonfieldDivision of Neurosurgery, Department of Surgery, BC Children's Hospital and University of British Columbia, 4480 Oak Street, Vancouver, BC, V6H 3 V4, Canada. bonfieldcm@gmail.com.
Paul SteinbokDivision of Neurosurgery, Department of Surgery, BC Children's Hospital and University of British Columbia, 4480 Oak Street, Vancouver, BC, V6H 3 V4, Canada.
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCerebellar astrocytomas (CA) are one of the most common posterior fossa tumors in children. The vast majority is low grade, and prognosis for long-term survival is excellent.

methodsRecent literature about CA was reviewed to provide an up to date overview of the epidemiology, pathology, molecular and cell biology, diagnosis, presentation, management, and long-term outcomes.

resultsSurgical resection remains the first-line treatment with complete removal of the tumor the goal. However, even when only subtotal resection has been achieved, there is a significant chance that the tumor will remain stable or will regress spontaneously. Adjuvant chemotherapy is reserved for those tumors that progress despite surgery, and more personalized chemotherapy is being pursued with better understanding of the molecular genetics of this tumor. Radiotherapy has generally not been recommended, but stereotactic radiotherapy and conformal proton beam radiotherapy may be reasonable options in the setting of relapse or progression. In the long term, permanent neurologic deficits, mainly cerebellar dysfunction, are common, but quality of life and cognitive function are generally good.

conclusionsLow-grade CA remains primarily a surgical disease, with excellent survival rates. Care must be taken with surgery and adjuvant treatments to preserve neurologic function to allow for optimal outcomes in the long term.

Indexed as

AstrocytomaCerebellar NeoplasmsPediatricsDatabases, BibliographicHumansNeurosurgeryBrain tumorCerebellar astrocytomaNeurosurgeryOutcomePediatricTreatment

Identifiers

PMID26351221
OpenAlexW2114493564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.