ArticleJournal of clinical laboratory analysis2016
Loop-Mediated Isothermal Amplification as a Fast Noninvasive Method of Helicobacter pylori Diagnosis.
Article in Journal of clinical laboratory analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Prevalence of Helicobacter pylori resistance to certain antibiotics at An-Najah University Hospital: a cross-sectional study.Scientific reports · 2024Article
- Antibiotic Resistance ofJournal of Korean medical science · 2024Review
- Loop-Mediated Isothermal Amplification (LAMP): Potential Point-of-Care Testing for Vulvovaginal Candidiasis.Journal of fungi (Basel, Switzerland) · 2023Article
- Review
- Efficacy of Loop-Mediated Isothermal Amplification forDiagnostics (Basel, Switzerland) · 2021Article
- What Is New inJournal of clinical medicine · 2021Review
- Identification and functional annotation of metabolism-associated lncRNAs and their related protein-coding genes in gastric cancer.Molecular genetics & genomic medicine · 2018Article
- Antibiotic resistance of Helicobacter pylori to 16 antibiotics in clinical patients.Journal of clinical laboratory analysis · 2018Article
- Loop-mediated isothermal amplification (LAMP): a versatile technique for detection of micro-organisms.Journal of applied microbiology · 2018Review
- Global circular RNA expression profile of human gastric cancer and its clinical significance.Cancer medicine · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHelicobacter pylori infection is etiologically associated with some important health problems such as gastric cancer. Because of the high clinical importance of H. pylori infection, development of a noninvasive test for the detection of H. pylori is desirable.
methodsIn this study, a loop-mediated isothermal amplification (LAMP) targeted ureC of H. pylori was evaluated on 100 stool specimens and compared with a stool antigen test. Culture and rapid urease test were considered as gold standards.
resultsThe overall detection rate of the fecal antigen test and LAMP was 58% and 82%, respectively. The analytical sensitivity of the fecal antigen test and LAMP was 500 and 10 H. pylori cells/g and 10 fg DNA/reaction, which is equal to six H. pylori genome.
conclusionLAMP technique has been characterized by high sensitivity and low detection limit for the detection of H. pylori in stool specimen. Clinical diagnostic performance of LAMP was better than the stool antigen test.
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