Evidence map›Paper›PMID 26351141›Full record

ArticleAmerican journal of industrial medicine2015

Isocyanates and work-related asthma: Findings from California, Massachusetts, Michigan, and New Jersey, 1993-2008.

Daniel Lefkowitz, Elise Pechter, Kathleen Fitzsimmons, Margaret Lumia, Alicia C Stephens, Letitia Davis, Jennifer Flattery, Justine Weinberg, Robert J Harrison, Mary Jo Reilly and 3 more

Abstract read
In one paragraph

Article in American journal of industrial medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Environmentally friendly splints for limb immobilisation: a systematic review.Annals of the Royal College of Surgeons of England · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Use of population data for assessing trends in work-related asthma mortality.Current opinion in allergy and clinical immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Daniel LefkowitzEnvironmental & Occupational Health Surveillance Program, New Jersey Department of Health, Trenton, New Jersey.
Elise PechterOccupational Health Surveillance Program, Massachusetts Department of Public Health, Boston, Massachusetts.
Kathleen FitzsimmonsOccupational Health Surveillance Program, Massachusetts Department of Public Health, Boston, Massachusetts.
Margaret LumiaEnvironmental & Occupational Health Surveillance Program, New Jersey Department of Health, Trenton, New Jersey.
Alicia C StephensEnvironmental & Occupational Health Surveillance Program, New Jersey Department of Health, Trenton, New Jersey.
Letitia DavisOccupational Health Surveillance Program, Massachusetts Department of Public Health, Boston, Massachusetts.
Jennifer FlatteryOccupational Health Branch, California Department of Public Health, Richmond, California.
Justine WeinbergPublic Health Institute, Contractor to California Department of Public Health, Richmond, California.
Robert J HarrisonOccupational Health Branch, California Department of Public Health, Richmond, California.
Mary Jo ReillyDivision of Occupational and Environmental Medicine, Michigan State University, East Lansing, Michigan.
Margaret S FiliosDivision of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia.
Gretchen E WhiteDivision of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia.
Kenneth D RosenmanDivision of Occupational and Environmental Medicine, Michigan State University, East Lansing, Michigan.

Funding

Expanded Program in Occupational Injury and Illness SurveillanceU60OH008466 · OH · MICHIGAN STATE UNIVERSITY · PI HARDUAR MORANO, LAUREL · 2005 to 2025
$16.4M
California Work-Related Injury Fatality ProgramU60OH008468 · OH · PUBLIC HEALTH INSTITUTE · PI HARRISON, ROBERT J · 2005 to 2025
$16.0M
Expanded Occupational Health Surveillance in MassachusettsU60OH008490 · OH · MASSACHUSETTS STATE DEPT OF PUB HEALTH · PI SPARER-FINE, EMILY HELEN · 2005 to 2025
$14.3M
NJ Occupational Health SurveillanceU60OH008485 · OH · NEW JERSEY STATE DEPT/HEALTH/SENIOR SRVS · PI LEFKOWITZ, DANIEL · 2005 to 2025
$5.5M
Intramural CDC HHS CC999999NIOSH CDC HHS U60 OH 008466NIOSH CDC HHS U60 OH008466NIOSH CDC HHS U60 OH 008468NIOSH CDC HHS U60 OH008468NIOSH CDC HHS U60 OH 008485NIOSH CDC HHS U60 OH008485NIOSH CDC HHS U60 OH 008490NIOSH CDC HHS U60 OH008490
6 · The paper itself

Abstract

backgroundIsocyanates remain a leading cause of work-related asthma (WRA).

methodsTwo independent data systems were analyzed for the period 1993-2008: (1) State-based WRA case surveillance data on persons with isocyanate-induced WRA from four states, and (2) Occupational Safety and Health Administration (OSHA) Integrated Management Information System (IMIS) isocyanate air sampling results.

resultsWe identified 368 cases of isocyanate-induced WRA from 32 industries and 678 OSHA isocyanate air samples with detectable levels from 31 industries. Seventeen industries were unique to one or the other dataset.

conclusionIsocyanate-induced WRA continues to occur in a wide variety of industries. Two data systems uncovered industries with isocyanate exposures and/or illness. Improved control measures and standards, including medical surveillance, are needed. More emphasis is needed on task-specific guidance, spill clean-up procedures, skin and respiratory protection, and targeted medical monitoring to mitigate the hazards of isocyanate use.

Indexed as

AdolescentAdultAgedAir Pollutants, OccupationalAsthma, OccupationalCaliforniaCenters for Disease Control and Prevention, U.S.FemaleHumansIsocyanatesMaleMassachusettsMichiganMiddle AgedNational Institute for Occupational Safety and Health, U.S.New JerseyAir Pollutants, OccupationalIsocyanatesisocyanatesoccupational disease preventionoccupational health surveillancework-related asthma

Identifiers

PMID26351141
PMCPMC4697263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.