Evidence map›Paper›PMID 26351037›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2016

Comparison between two assessment methods for exercise-induced laryngeal obstructions.

Katarina Norlander, Pernille M Christensen, Robert C Maat, Thomas Halvorsen, John Helge Heimdal, Staffan Morén, Niels Rasmussen, Leif Nordang

Registry-linked trialAbstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04620343 (Exercise Induced Laryngeal Obstruction; a Randomized Controlled Treatment Trial), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04620343 narecruitingnot on this mapstarted 2021, after this paper: background citation

Exercise Induced Laryngeal Obstruction; a Randomized Controlled Treatment Trial

TypeinterventionalSponsorHaukeland University HospitalRan2021 to 2036Enrolled350ConditionsExercise Induced Laryngeal Obstruction (EILO)ArmsA: Breathing advice with bio-feedback, B: Breathing advice with bio-feedback, Inspiratory muscle training (IMT), C: Breathing advice with bio-feedback, Speech Therapy, D: Breathing advice with bio-feedback, IMT and Speech Therapy, A: If CLE-test unchanged, additional IMT and Speech Therapy
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Speech therapy for exercise-induced laryngeal obstruction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  7. Conundrums in the breathless athlete; exercise-induced laryngeal obstruction or asthma?Scandinavian journal of medicine & science in sports · 2022
    Article
  8. Article
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  13. Differentiating vocal cord dysfunction from asthma.Journal of asthma and allergy · 2017
    Review
  14. Review
  15. Comparison between two assessment methods for exercise-induced laryngeal obstructions.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Katarina NorlanderDepartment of Surgical Sciences, Otorhinolaryngology and Head and Neck Surgery, Uppsala University, Akademiska Sjukhuset, 751 85, Uppsala, Sweden.
Pernille M ChristensenDepartment of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen E, Denmark. p.christensen@dadlnet.dk.
Robert C MaatDepartment of Otolaryngology, Röpcke-Zweers Hospital, Jan Weitkamplaan 4 a, Hardenberg, The Netherlands.
Thomas HalvorsenDepartment of Pediatrics, Haukeland University Hospital, Jonas Lies vei 65, 5021, Bergen, Norway.
John Helge HeimdalDepartment of Otolaryngology-Head and Neck Surgery, Haukeland University Hospital, Jonas Lies vei 65, 5021, Bergen, Norway.
Staffan MorénDepartment of Surgical Sciences, Otorhinolaryngology and Head and Neck Surgery, Uppsala University, Akademiska Sjukhuset, 751 85, Uppsala, Sweden.
Niels RasmussenDepartment of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen E, Denmark.
Leif NordangDepartment of Surgical Sciences, Otorhinolaryngology and Head and Neck Surgery, Uppsala University, Akademiska Sjukhuset, 751 85, Uppsala, Sweden.
Uppsala University Hospital · SEHaukeland University Hospital · NORigshospitalet · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise-induced laryngeal obstructions (E-ILOs) are important differential diagnoses to exercise-induced asthma and are diagnosed by the continuous laryngoscopy exercise (CLE) test. There are two different methods for evaluating the severity of E-ILOs using recordings from the CLE test; the CLE score and EILOMEA. The aim of this study was to investigate the consistency between these methods. Using their respective method, the developers of each method evaluated 60 laryngoscopic recordings from patients with different subtypes and various levels of severity of E-ILOs. The CLE score evaluates glottic and supraglottic obstructions on a 4-grade scale. EILOMEA uses software to calculate the obstruction severity on continuous scales from a still frame of the larynx during maximal obstruction giving three parameters reflecting glottic and supraglottic obstruction. The means of the EILOMEA measures differed significantly for CLE score 1 vs. 2 and 2 vs. 3, but not for 0 vs. 1 for glottic as well as supraglottic obstructions. The EILOMEA method does not distinguish between CLE score 0 and 1, but otherwise the methods correlate. Since previous studies have suggested that only CLE scores of 2 and 3 reflect a severity of E-ILOs of clinical importance, this lack of the EILOMEA method is not crucial for a correct medical evaluation.

Indexed as

AdultAirway ObstructionAsthma, Exercise-InducedDiagnosis, DifferentialExercise TestFemaleFollow-Up StudiesHumansLaryngeal DiseasesLaryngoscopyMaleCLE scoreContinuous laryngoscopy exercise testE-ILOEILOMEAExercise-induced respiratory difficulties

Identifiers

PMID26351037
OpenAlexW2156218214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.