Evidence map›Paper›PMID 26351036›Full record

ArticleClinical imaging

The relationship of breast density in mammography and magnetic resonance imaging in high-risk women and women with breast cancer.

Marissa Albert, Freya Schnabel, Jennifer Chun, Shira Schwartz, Jiyon Lee, Ana Paula Klautau Leite, Linda Moy

Abstract read
In one paragraph

Article in Clinical imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Concurrent water TMagnetic resonance imaging · 2025
    Article
  5. Review
  6. The Associations between Intakes of One-Carbon Metabolism-Related Vitamins and Breast Density among Young Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marissa AlbertDepartment of Radiology, New York University Langone Medical Center, Perlmutter Cancer Center, 160 East 34th Street, New York, NY 10016, USA.
Freya SchnabelDepartment of Surgery, New York University Langone Medical Center, Perlmutter Cancer Center, 160 East 34th Street, New York, NY 10016, USA.
Jennifer ChunDepartment of Surgery, New York University Langone Medical Center, Perlmutter Cancer Center, 160 East 34th Street, New York, NY 10016, USA.
Shira SchwartzDepartment of Surgery, New York University Langone Medical Center, Perlmutter Cancer Center, 160 East 34th Street, New York, NY 10016, USA.
Jiyon LeeDepartment of Radiology, New York University Langone Medical Center, Perlmutter Cancer Center, 160 East 34th Street, New York, NY 10016, USA.
Ana Paula Klautau LeiteDepartment of Radiology, Hospital das Clínicas, School of Medicine, University of São Paulo, São Paulo, Brazil 05024-000 SP.
Linda MoyDepartment of Radiology, New York University Langone Medical Center, Perlmutter Cancer Center, 160 East 34th Street, New York, NY 10016, USA. Electronic address: Linda.Moy@nyumc.org.

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
NCI NIH HHS P30 CA016087
6 · The paper itself

Abstract

purposeTo evaluate the relationship between mammographic breast density (MBD), background parenchymal enhancement (BPE), and fibroglandular tissue (FGT) in women with breast cancer (BC) and at high risk for developing BC.

methodsOur institutional database was queried for patients who underwent mammography and MRI.

resultsFour hundred three (85%) had BC and 72 (15%) were at high risk. MBD (P=.0005), BPE (P<.0001), and FGT (P=.02) were all higher in high-risk women compared to the BC group.

conclusionsHigher levels of MBD, BPE and FGT are seen in women at higher risk for developing BC when compared to women with BC.

Indexed as

AdultAgedAged, 80 and overBreast DensityBreast NeoplasmsDatabases, FactualFemaleHumansMagnetic Resonance ImagingMammary Glands, HumanMammographyMiddle AgedRetrospective StudiesYoung AdultBPEBreast cancerDensityMRI

Identifiers

PMID26351036
PMCPMC4686383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.