ArticleScientific reports2015
Bacteriophages of wastewater foaming-associated filamentous Gordonia reduce host levels in raw activated sludge.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 87 citations in OpenAlex.
- Phage Cocktail Designed for Wastewater Bioremediation Has Limited Effect on Crustacean Filtrator Microbiome Diversity and Health.Environmental microbiology reports · 2026Article
- Metaproteomics in the One Health framework for unraveling microbial effectors in microbiomes.Microbiome · 2025Review
- Two novel bacteriophages isolated from the environment that can help control activated sludge foaming.Folia microbiologica · 2024Article
- Benefits and Challenges of Applying Bacteriophage Biocontrol in the Consumer Water Cycle.Microorganisms · 2024Review
- Efficacy and clinical potential of phage therapy in treating methicillin-resistant Staphylococcus aureus (MRSA) infections: A review.European journal of microbiology & immunology · 2024Review
- Tools and methodology toFrontiers in microbiology · 2024Review
- Bacteriophage-mediated approaches for biofilm control.Frontiers in cellular and infection microbiology · 2024Review
- Nonbacterial Microflora in Wastewater Treatment Plants: an Underappreciated Potential Source of Pathogens.Microbiology spectrum · 2023Article
- Escherichia coli ST155 as a production-host of three different polyvalent phages and their characterisation with a prospect for wastewater disinfection.Scientific reports · 2022Article
- Lytics broadcasting system: A novel approach to disseminate bacteriophages for disinfection and biogenic hydrogen sulphide removal tested in synthetic sewage.Results in engineering · 2022Article
- Bacteriophages in sewage: abundance, roles, and applications.FEMS microbes · 2022Article
- Prokaryotic viruses impact functional microorganisms in nutrient removal and carbon cycle in wastewater treatment plants.Nature communications · 2021Article
- pdm_utils: a SEA-PHAGES MySQL phage database management toolkit.Bioinformatics (Oxford, England) · 2021Article
- Article
- Bacteriophage ecology in biological wastewater treatment systems.Applied microbiology and biotechnology · 2021Review
- Microbial predation accelerates granulation and modulates microbial community composition.BMC microbiology · 2021Article
- Long-run bacteria-phage coexistence dynamics under natural habitat conditions in an environmental biotechnology system.The ISME journal · 2021Article
- Bacteriophages in Biological Wastewater Treatment Systems: Occurrence, Characterization, and Function.Frontiers in microbiology · 2021Review
- Bacteriophages in water pollution control: Advantages and limitations.Frontiers of environmental science & engineering · 2021Article
- Bacteriophages in Natural and Artificial Environments.Pathogens (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Filamentous bacteria are a normal and necessary component of the activated sludge wastewater treatment process, but the overgrowth of filamentous bacteria results in foaming and bulking associated disruptions. Bacteriophages, or phages, were investigated for their potential to reduce the titer of foaming bacteria in a mixed-microbial activated sludge matrix. Foaming-associated filamentous bacteria were isolated from activated sludge of a commercial wastewater treatment plan and identified as Gordonia species by 16S rDNA sequencing. Four representative phages were isolated that target G. malaquae and two un-named Gordonia species isolates. Electron microscopy revealed the phages to be siphophages with long tails. Three of the phages--GordTnk2, Gmala1, and GordDuk1--had very similar ~76 kb genomes, with >93% DNA identity. These genomes shared limited synteny with Rhodococcus equi phage ReqiDocB7 and Gordonia phage GTE7. In contrast, the genome of phage Gsput1 was smaller (43 kb) and was not similar enough to any known phage to be placed within an established phage type. Application of these four phages at MOIs of 5-15 significantly reduced Gordonia host levels in a wastewater sludge model by approximately 10-fold as compared to non-phage treated reactors. Phage control was observed for nine days after treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.