Evidence map›Paper›PMID 26349573›Full record

ArticleLa Radiologia medica2016

Role of WB-MR/DWIBS compared to (18)F-FDG PET/CT in the therapy response assessment of lymphoma.

Nicola Maggialetti, Cristina Ferrari, Carla Minoia, Artor Niccoli Asabella, Michele Ficco, Giacomo Loseto, Giacomina De Tullio, Vincenza de Fazio, Angela Calabrese, Attilio Guarini and 2 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in La Radiologia medica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. PET/MRI in Pediatric Neuroimaging: Primer for Clinical Practice.AJNR. American journal of neuroradiology · 2022
    Review
  6. Whole-body MRI versus an [European radiology · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. MRI and PET/MRI in hematologic malignancies.Journal of magnetic resonance imaging : JMRI · 2020
    Review
  12. Article
  13. Review
  14. Review
  15. Radiofrequency ablation of osteoid osteoma.Acta bio-medica : Atenei Parmensis · 2018
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Comparative Study betweenIndian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Nicola MaggialettiDepartment of Medicine and Health Science, University of Molise, Campobasso, Italy. n.maggialetti@gmail.com.
Cristina FerrariD.I.M.- Diagnostic Imaging - Nuclear Medicine, University of Bari "Aldo Moro", Bari, Italy.
Carla MinoiaDepartment of Medical and Experimental Oncology, IRCCS National Cancer Research Centre "Giovanni Paolo II", Bari, Italy.
Artor Niccoli AsabellaD.I.M.- Diagnostic Imaging - Nuclear Medicine, University of Bari "Aldo Moro", Bari, Italy.
Michele FiccoDepartment of Radiodiagnostic, IRCCS National Cancer Research Centre "Giovanni Paolo II", Bari, Italy.
Giacomo LosetoDepartment of Medical and Experimental Oncology, IRCCS National Cancer Research Centre "Giovanni Paolo II", Bari, Italy.
Giacomina De TullioDepartment of Medical and Experimental Oncology, IRCCS National Cancer Research Centre "Giovanni Paolo II", Bari, Italy.
Vincenza de FazioDepartment of Medical and Experimental Oncology, IRCCS National Cancer Research Centre "Giovanni Paolo II", Bari, Italy.
Angela CalabreseDepartment of Radiodiagnostic, IRCCS National Cancer Research Centre "Giovanni Paolo II", Bari, Italy.
Attilio GuariniDepartment of Medical and Experimental Oncology, IRCCS National Cancer Research Centre "Giovanni Paolo II", Bari, Italy.
Giuseppe RubiniD.I.M.- Diagnostic Imaging - Nuclear Medicine, University of Bari "Aldo Moro", Bari, Italy.
Luca BruneseDepartment of Medicine and Health Science, University of Molise, Campobasso, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Bari Aldo Moro · ITUniversity of Molise · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study prospectively evaluated whole-body magnetic resonance/diffusion-weighted imaging with body signal suppression (WB-MR/DWIBS) reliability compared to (18)F-FDG PET/CT in the treatment response assessment of classic Hodgkin lymphomas (HL) and aggressive non-Hodgkin lymphomas (aNHL). MATERIALS AND

methodsTwenty-seven consecutive patients were prospectively enrolled at the time of diagnosis. Eighteen (11 HL and seven aNHL) were considered for the analysis. They received chemo/radiotherapy as induction and completed post-treatment evaluation performing both (18)F-FDG PET/CT and WB-MR/DWIBS. The revised response criteria for malignant lymphomas were used to assess the response to treatment. We evaluated the agreement between the two methods by Cohen's K test. Post-therapy WB-MR/DWIBS sensitivity, specificity, PPV, NPV and accuracy were then calculated, considering the 12 months of follow-up period as the gold standard.

resultsBy using an evaluation on a lesion-by-lesion basis, WB-MR/DWIBS and (18)F-FDG PET/CT showed an overall good agreement (K = 0.796, 95% IC = 0.651-0.941), especially in the evaluation of the nodal basins in aNHL (K = 0.937, 95% IC = 0.814-1). In reference to the revised response criteria for malignant lymphomas, the two methods showed a good agreement (K = 0.824, 95% IC = 0.493-1). Post-therapy sensitivity, specificity, PPV, NPV and accuracy of WB-MR/DWIBS were 43, 91, 75, 71 and 72%, respectively.

conclusionWB-MR/DWIBS seems to be an appropriate method for the post-treatment assessment of patients affected by HL and aNHL. The small discrepancies between the two methods found within HL could be due to the biological and metabolic behavior of this group of diseases. Larger prospective studies are necessary to better define the role of WB-MR/DWIBS in this setting of patients.

Indexed as

Diffusion Magnetic Resonance ImagingMagnetic Resonance ImagingMultimodal ImagingPositron-Emission TomographyTomography, X-Ray ComputedWhole Body ImagingAdultAgedAged, 80 and overFemaleFluorodeoxyglucose F18Hodgkin DiseaseHumansLymphoma, Non-HodgkinMaleMiddle AgedFluorodeoxyglucose F18Radiopharmaceuticals18F-FDG PET/CTHodgkin lymphomaNon-Hodgkin lymphomaRevised response criteria for malignant lymphomaTherapy responseWB-MR/DWIBS

Identifiers

PMID26349573
OpenAlexW2110486280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.