Evidence map›Paper›PMID 26349572›Full record

ArticleLa Radiologia medica2016

Effectiveness of Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) in the uterine adenomyosis treatment: technical approach and MRI evaluation.

Fabiana Ferrari, Francesco Arrigoni, Anna Miccoli, Sara Mascaretti, Eva Fascetti, Giulio Mascaretti, Antonio Barile, Carlo Masciocchi

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In one paragraph

Article in La Radiologia medica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
8.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 55 citations in OpenAlex.

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  18. Advances in diagnostic and interventional radiology.Acta bio-medica : Atenei Parmensis · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fabiana FerrariDipartimento di Scienze Cliniche Applicate E Biotecnologiche, University of L'Aquila-San Salvatore Hospital, Via Lorenzo Natali, 67100, L'Aquila, Italy. fabianaferrari@hotmail.it.
Francesco ArrigoniDipartimento di Scienze Cliniche Applicate E Biotecnologiche, University of L'Aquila-San Salvatore Hospital, Via Lorenzo Natali, 67100, L'Aquila, Italy.
Anna MiccoliDipartimento di Scienze Cliniche Applicate E Biotecnologiche, University of L'Aquila-San Salvatore Hospital, Via Lorenzo Natali, 67100, L'Aquila, Italy.
Sara MascarettiDipartimento di Scienze Cliniche Applicate E Biotecnologiche, University of L'Aquila-San Salvatore Hospital, Via Lorenzo Natali, 67100, L'Aquila, Italy.
Eva FascettiDipartimento di Scienze Cliniche Applicate E Biotecnologiche, University of L'Aquila-San Salvatore Hospital, Via Lorenzo Natali, 67100, L'Aquila, Italy.
Giulio MascarettiDipartimento di Scienze Cliniche Applicate E Biotecnologiche, University of L'Aquila-San Salvatore Hospital, Via Lorenzo Natali, 67100, L'Aquila, Italy.
Antonio BarileDipartimento di Scienze Cliniche Applicate E Biotecnologiche, University of L'Aquila-San Salvatore Hospital, Via Lorenzo Natali, 67100, L'Aquila, Italy.
Carlo MasciocchiDipartimento di Scienze Cliniche Applicate E Biotecnologiche, University of L'Aquila-San Salvatore Hospital, Via Lorenzo Natali, 67100, L'Aquila, Italy.
University of L'Aquila · ITSan Salvatore Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the treatment efficacy of uterine adenomyosis using MRgFUS as a mini-invasive therapy. MATERIALS AND

methodsTwenty-three patients affected by symptomatic uterine adenomyosis (11 focal and 7 diffuse forms), diagnosed using MRI, were included in this study. Eighteen out of 23 were submitted to MRgFUS. All junctional zone more than 12 mm in width were considered to be adenomyosis. Study evaluates the pre-treatment target volume measured prior to the treatment on the CE T1-weighted sequence and the MRgFUS-treated volume (MRgFUS-TV), represented by the volume of the lesion ablated, measured directly by means of the MRgFUS. The treated volume on the CE T1-weighted sequence (CE MRI-TV) was measured immediately after treatment. After 1 year, the junctional zone thickness was measured in order to compare pre- and post-treatment values. The therapeutic plan consisted of a high-energy-grid sonication. Symptomatology was assessed through the UFS-QOL.

resultsThe pre-treatment target volume mean value was of 59.7 cc; the MRgFUS-TV had a mean value of 44.9 cc, and the mean value of CE MRI-TV, measured immediately after treatment, was of 52.8 cc, with an increase of 13.7%. The 86.5% of the lesion was treated. After 1 year from the treatment, 15/18 (83%) patients showed thickness of the junctional zone <12 mm; 3/18 (17%) had a junctional zone >12 mm.

conclusionMRgFUS is an encouraging mini-invasive treatment for adenomyosis that permits to maintain the integrity of the uterus in a pathology with limited therapeutic possibility.

Indexed as

Magnetic Resonance ImagingAdenomyosisAdultFemaleHumansMiddle AgedUltrasonic Surgical ProceduresYoung AdultAdenomyosisHIFUMini-invasive treatmentMRgFUSUterine fibroids

Identifiers

PMID26349572
OpenAlexW1680353569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.