ArticleJournal of developmental and behavioral pediatrics : JDBP2015
Functional and Anatomic Consequences of Diabetic Pregnancy on Memory in Ten-Year-Old Children.
Article in Journal of developmental and behavioral pediatrics : JDBP, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- A meta-analysis of the relation between hippocampal volume and memory ability in typically developing children and adolescents.Hippocampus · 2022Pooled it
- Cost-effectiveness of iron deficiency screening in pregnancy across ferritin-based thresholds.Blood advances · 2026Article
- Article
- Prenatal maternal diabetes, comorbidities, and risk for neurodevelopmental impairment in the first two years.Pediatric research · 2025Article
- Early life stress and iron metabolism in developmental psychoneuroimmunology.Brain, behavior, & immunity - health · 2024Article
- Associations among prenatal exposure to gestational diabetes mellitus, brain structure, and child adiposity markers.Obesity (Silver Spring, Md.) · 2023Article
- The Interaction between Psychological Stress and Iron Status on Early-Life Neurodevelopmental Outcomes.Nutrients · 2023Review
- The importance of iron deficiency in pregnancy on fetal, neonatal, and infant neurodevelopmental outcomes.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023Review
- The impact of maternal diabetes on the future health and neurodevelopment of the offspring: a review of the evidence.Frontiers in endocrinology · 2023Review
- No Clinically Relevant Memory Effects in Perinatal Hyperglycemia and Hypoglycemia: A 40-Year Follow-Up of a Small Cohort.Frontiers in public health · 2022Article
- Selective morphological and volumetric alterations in the hippocampus of children exposed in utero to gestational diabetes mellitus.Human brain mapping · 2021Article
- Sex differences in the association between prenatal exposure to maternal obesity and hippocampal volume in children.Brain and behavior · 2020Article
- Atypical fetal development: Fetal alcohol syndrome, nutritional deprivation, teratogens, and risk for neurodevelopmental disorders and psychopathology.Development and psychopathology · 2018Review
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
objectivePregnancies complicated by diabetes mellitus impair offspring memory functions during infancy and early childhood. The purpose of this study was to investigate the long-term consequences of such pregnancies on memory and memory-related brain regions in 10-year-old children.
methodsNineteen children of diabetic mothers (CDMs) and 35 children of nondiabetic mothers participated in this 10-year follow-up study. Memory performance was assessed using a continuous recognition memory task during which children made old/new judgments in response to pictures of concrete and abstract objects presented after different lags or delays. In addition, the volume of the hippocampal formation (HF) was measured using high-resolution structural images.
resultsAt 10 years of age, recognition memory performance of CDMs did not differ from children of nondiabetic mothers. Similarly, the volume of the HF did not differ between groups. However, the size of the HF in CDMs predicted the time those children needed to provide accurate responses in the continuous recognition memory task.
conclusionsCDMs do not show memory impairments by 10 years of age, despite evidence for such impairments early in life. However, subtle differences in underlying neural processes may still be present. These results have important implications for long-term cognitive development of CDMs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.