ArticlePLoS genetics2015
The Chromatin Protein DUET/MMD1 Controls Expression of the Meiotic Gene TDM1 during Male Meiosis in Arabidopsis.
Article in PLoS genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 60 citations in OpenAlex.
- Meiotic cytokinesis defects in cultured Arabidopsis flowers induce diploid microspores.Plant reproduction · 2025Article
- Sporophyte-directed gametogenesis in Arabidopsis.Nature plants · 2025Article
- Genome-Wide Identification and Expression Analysis of the PHD Finger Gene Family in Pea (Plants (Basel, Switzerland) · 2024Article
- PHD finger proteins function in plant development and abiotic stress responses: an overview.Frontiers in plant science · 2023Review
- MS1/MMD1 homologues in the moss Physcomitrium patens are required for male and female gametogenesis.The New phytologist · 2022Article
- Pentaploidization Enriches the Genetic Diversity of Wheat by Enhancing the Recombination of AB Genomes.Frontiers in plant science · 2022Article
- An insight into understanding the coupling between homologous recombination mediated DNA repair and chromatin remodeling mechanisms in plant genome: an update.Cell cycle (Georgetown, Tex.) · 2021Review
- Article
- Comparison of Metabolic Profiling ofPhenomics (Cham, Switzerland) · 2021Article
- Response of phytohormone mediated plant homeodomain (PHD) family to abiotic stress in upland cotton (Gossypium hirsutum spp.).BMC plant biology · 2021Article
- Cell-type-dependent histone demethylase specificity promotes meiotic chromosome condensation in Arabidopsis.Nature plants · 2020Article
- The cohesin loader SCC2 contains a PHD finger that is required for meiosis in land plants.PLoS genetics · 2020Article
- Comparative transcript profiling and cytological observation of the newly bred recessive genic male sterility non-heading Chinese cabbage (Brassica rapa ssp. chinensis) line WS24-3A.Genes & genomics · 2019Article
- TDR INTERACTING PROTEIN 3, encoding a PHD-finger transcription factor, regulates Ubisch bodies and pollen wall formation in rice.The Plant journal : for cell and molecular biology · 2019Article
- Mutation in a PHD-finger protein MS4 causes male sterility in soybean.BMC plant biology · 2019Article
- Tapetum-Dependent Male Meiosis Progression in Plants: Increasing Evidence Emerges.Frontiers in plant science · 2019Review
- Fine mapping of a male sterility gene ms-3 in a novel cucumber (Cucumis sativus L.) mutant.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Insights Into the Role of Ubiquitination in Meiosis: Fertility, Adaptation and Plant Breeding.The arabidopsis book · 2018Article
- SDG2-Mediated H3K4me3 Is Crucial for Chromatin Condensation and Mitotic Division during Male Gametogenesis in Arabidopsis.Plant physiology · 2017Article
- Down-Regulation ofFrontiers in plant science · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Meiosis produces haploid cells essential for sexual reproduction. In yeast, entry into meiosis activates transcription factors which trigger a transcriptional cascade that results in sequential co-expression of early, middle and late meiotic genes. However, these factors are not conserved, and the factors and regulatory mechanisms that ensure proper meiotic gene expression in multicellular eukaryotes are poorly understood. Here, we report that DUET/MMD1, a PHD finger protein essential for Arabidopsis male meiosis, functions as a transcriptional regulator in plant meiosis. We find that DUET-PHD binds H3K4me2 in vitro, and show that this interaction is critical for function during meiosis. We also show that DUET is required for proper microtubule organization during meiosis II, independently of its function in meiosis I. Remarkably, DUET protein shows stage-specific expression, confined to diplotene. We identify two genes TDM1 and JAS with critical functions in cell cycle transitions and spindle organization in male meiosis, as DUET targets, with TDM1 being a direct target. Thus, DUET is required to regulate microtubule organization and cell cycle transitions during male meiosis, and functions as a direct transcription activator of the meiotic gene TDM1. Expression profiling showed reduced expression of a subset comprising about 12% of a known set of meiosis preferred genes in the duet mutant. Our results reveal the action of DUET as a transcriptional regulator during male meiosis in plants, and suggest that transcription of meiotic genes is under stagewise control in plants as in yeast.
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