Evidence map›Paper›PMID 26348136›Full record

ArticleThe Journal of steroid biochemistry and molecular biology2016

Selective regulation of Mmp13 by 1,25(OH)

Mark B Meyer, Nancy A Benkusky, Melda Onal, J Wesley Pike

Open access · greenAbstract read
In one paragraph

Article in The Journal of steroid biochemistry and molecular biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Genomic mechanisms controlling renal vitamin D metabolism.The Journal of steroid biochemistry and molecular biology · 2023
    Article
  3. Review
  4. Article
  5. TheeLife · 2021
    Article
  6. Article
  7. Review
  8. Zoological research · 2018
    Review
  9. Article
  10. Biology and Mechanisms of Action of the Vitamin D Hormone.Endocrinology and metabolism clinics of North America · 2017
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research.Arteriosclerosis, thrombosis, and vascular biology · 2016
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mark B MeyerUniversity of Wisconsin at Madison, Madison, WI 53706, USA. Electronic address: mmeyer@biochem.wisc.edu.
Nancy A BenkuskyUniversity of Wisconsin at Madison, Madison, WI 53706, USA.
Melda OnalUniversity of Wisconsin at Madison, Madison, WI 53706, USA.
J Wesley PikeUniversity of Wisconsin at Madison, Madison, WI 53706, USA.
University of Wisconsin–Madison · US

Funding

Dynamic Mechanisms of Vitamin D-Induced Gene ExpressionR01DK072281 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI PIKE, J WESLEY · 2005 to 2012
$2.6M
NIDDK NIH HHS R01 DK072281
6 · The paper itself

Abstract

Matrix metalloproteinase 13 (MMP13, collagenase-3) is a vital component for chondrocyte and osteoblast maturation, and is aberrantly expressed in numerous disease states. At the transcriptional level, Mmp13 is controlled by many different growth factors and hormones. Most notably, Mmp13 is regulated by the vitamin D hormone (1,25(OH)

Indexed as

Enhancer Elements, GeneticAnimalsCalcitriolCell LineClustered Regularly Interspaced Short Palindromic RepeatsCore Binding Factor Alpha 1 SubunitFemaleGene EditingGene Expression RegulationMaleMatrix Metalloproteinase 13MiceMice, KnockoutOsteoblastsParathyroid HormonePromoter Regions, GeneticCalcitriolCore Binding Factor Alpha 1 SubunitMatrix Metalloproteinase 13Mmp13 protein, mouseParathyroid HormoneReceptors, CalcitriolRunx2 protein, mouseSp7 protein, mouseSp7 Transcription FactorTranscription Factors1,25(OH)(2)D(3)ChIP-seqHistone modificationMmp13OsterixPTHRUNX2Sp7VDRVitamin D

Identifiers

PMID26348136
PMCPMC4779429
OpenAlexW1569143752

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.