Evidence map›Paper›PMID 26347885›Full record

ReviewBioMed research international2015

Research Advances in Tissue Engineering Materials for Sustained Release of Growth Factors.

Hai-yang Zhao, Jiang Wu, Jing-jing Zhu, Ze-cong Xiao, Chao-chao He, Hong-xue Shi, Xiao-kun Li, Shu-lin Yang, Jian Xiao

Abstract readReview
In one paragraph

Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hai-yang ZhaoSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China ; Molecular Pharmacology Research Center, Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Jiang WuMolecular Pharmacology Research Center, Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Jing-jing ZhuMolecular Pharmacology Research Center, Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Ze-cong XiaoMolecular Pharmacology Research Center, Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Chao-chao HeMolecular Pharmacology Research Center, Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Hong-xue ShiMolecular Pharmacology Research Center, Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Xiao-kun LiSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China ; Molecular Pharmacology Research Center, Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Shu-lin YangSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China.
Jian XiaoSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China ; Molecular Pharmacology Research Center, Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth factors are a class of cytokines that stimulate cell growth and are widely used in clinical practice, such as wound healing, revascularization, bone repair, and nervous system disease. However, free growth factors have a short half-life and are instable in vivo. Therefore, the search of excellent carriers to enhance sustained release of growth factors in vivo has become an area of intense research interest. The development of controlled-release systems that protect the recombinant growth factors from enzymatic degradation and provide sustained delivery at the injury site during healing should enhance the growth factor's application in tissue regeneration. Thus, this study reviews current research on commonly used carriers for sustained release of growth factors and their sustained release effects for preservation of their bioactivity and their accomplishment in tissue engineering approaches.

Indexed as

Drug ImplantsIntercellular Signaling Peptides and ProteinsAnimalsDelayed-Action PreparationsHumansRegenerationRegenerative MedicineTissue EngineeringDelayed-Action PreparationsDrug ImplantsIntercellular Signaling Peptides and Proteins

Identifiers

PMID26347885
PMCPMC4548067

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.