Evidence map›Paper›PMID 26347858›Full record

ArticleFrontiers in public health2015

Assessment of MALDI-TOF MS as Alternative Tool for Streptococcus suis Identification.

Marta Pérez-Sancho, Ana Isabel Vela, Teresa García-Seco, Marcelo Gottschalk, Lucas Domínguez, José Francisco Fernández-Garayzábal

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. AVeterinary sciences · 2026
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  5. Molecular Identification of Meningitis/Septicemia Due toDiagnostics (Basel, Switzerland) · 2025
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  7. Characterization of neurologic disease-associatedJournal of clinical microbiology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Distribution and characterization ofCanadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Case reports in nephrology · 2018
    Article
  18. Article
  19. Current Taxonomical Situation of Streptococcus suis.Pathogens (Basel, Switzerland) · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Marta Pérez-SanchoCentro de Vigilancia Sanitaria Veterinaria (VISAVET), Universidad Complutense , Madrid , Spain ; Campus de Excelencia Internacional (CEI) Moncloa, Universidad Politécnica de Madrid (UPM), Universidad Complutense de Madrid (UCM) , Madrid , Spain.
Ana Isabel VelaCentro de Vigilancia Sanitaria Veterinaria (VISAVET), Universidad Complutense , Madrid , Spain ; Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense , Madrid , Spain.
Teresa García-SecoCentro de Vigilancia Sanitaria Veterinaria (VISAVET), Universidad Complutense , Madrid , Spain.
Marcelo GottschalkGroupe de Recherche sur les Maladies Infectieuses du Porc, Faculté de Médecine Vétérinaire, Université de Montréal , Saint-Hyacinthe, QC , Canada.
Lucas DomínguezCentro de Vigilancia Sanitaria Veterinaria (VISAVET), Universidad Complutense , Madrid , Spain ; Campus de Excelencia Internacional (CEI) Moncloa, Universidad Politécnica de Madrid (UPM), Universidad Complutense de Madrid (UCM) , Madrid , Spain ; Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense , Madrid , Spain.
José Francisco Fernández-GarayzábalCentro de Vigilancia Sanitaria Veterinaria (VISAVET), Universidad Complutense , Madrid , Spain ; Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense , Madrid , Spain.
Universidad Complutense de Madrid · ESUniversidad Politécnica de Madrid · ESUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accuracy of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for identifying Streptococcus suis isolates obtained from pigs, wild animals, and humans was evaluated using a PCR-based identification assay as the gold standard. In addition, MALDI-TOF MS was compared with the commercial multi-tests Rapid ID 32 STREP system. From the 129 S. suis isolates included in the study and identified by the molecular method, only 31 isolates (24.03%) had score values ≥2.300 and 79 isolates (61.24%) gave score values between 2.299 and 2.000. After updating the currently available S. suis MALDI Biotyper database with the spectra of three additional clinical isolates of serotypes 2, 7, and 9, most isolates had statistically significant higher score values (mean score: 2.65) than those obtained using the original database (mean score: 2.182). Considering the results of the present study, we suggest using a less restrictive threshold score of ≥2.000 for reliable species identification of S. suis. According to this cut-off value, a total of 125 S. suis isolates (96.9%) were correctly identified using the updated database. These data indicate an excellent performance of MALDI-TOF MS for the identification of S. suis.

Indexed as

biochemical testsidentificationMALDI-TOF MSPCRStreptococcus suis

Identifiers

PMID26347858
PMCPMC4543777
OpenAlexW1747682610

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.