ReviewJournal of skin cancer2015
Oculocutaneous Albinism and Squamous Cell Carcinoma of the Skin of the Head and Neck in Sub-Saharan Africa.
Review in Journal of skin cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 65 citations in OpenAlex.
- The prevalence of epidermal skin malignancies in people living with oculocutaneous albinism attending the Universitas Academic Hospital, Bloemfontein, South Africa.Dermatology reports · 2026Article
- Mild Oculocutaneous Albinism Type 1B With Subtle Cutaneous Findings: A Dermatology-Oriented Case Report.Cureus · 2026Article
- Non-melanoma skin cancer and HPV in persons with albinism: a call for research investment.British journal of cancer · 2025Review
- Multiple Cutaneous Squamous Cell Carcinomas on Primary Epidermodysplasia Verruciformis in a 19-Year-Old Black Subject.Case reports in dermatological medicine · 2025Article
- Clinico-pathologic profile of skin cancers in oculocutaneous albinism at Universitas Academic Hospital.Health SA = SA Gesondheid · 2025Article
- What Have We Learned about the Prevention of NMSC from Albino Patients from Malawi? Secondary Prevention Maintained over Time.Cancers · 2024Article
- [A case for the inclusion of oculocutaneous albinism as a skin-related Neglected Tropical Disease].Medecine tropicale et sante internationale · 2023Article
- Unprotected: the consequences of climate change for the health of persons with albinism.BMJ global health · 2023Article
- Chondroitin Sulfate Proteoglycan 4 as a Marker for Aggressive Squamous Cell Carcinoma.Cancers · 2022Review
- Cutaneous and lip squamous cell carcinomas in an albinism patient: A case report.Annals of medicine and surgery (2012) · 2022Article
- Ophthalmological Manifestations of Oculocutaneous and Ocular Albinism: Current Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2022Review
- Identification of Biomarkers Associated with Cancerous Change in Oral Leukoplakia Based on Integrated Transcriptome Analysis.Journal of oncology · 2022Article
- Sociodemographic features of a cohort of people living with albinism in Botswana.JAAD international · 2021Article
- Phenylthiourea Binding to Human Tyrosinase-Related Protein 1.International journal of molecular sciences · 2020Article
- MITF and UV responses in skin: From pigmentation to addiction.Pigment cell & melanoma research · 2019Review
- Pigmentation and vision: Is GPR143 in control?Journal of neuroscience research · 2019Review
- Functional validation of the albinism-associated tyrosinase T373K SNP by CRISPR/Cas9-mediated homology-directed repair (HDR) in rabbits.EBioMedicine · 2018Article
- Global Skin Disease Morbidity and Mortality: An Update From the Global Burden of Disease Study 2013.JAMA dermatology · 2017Article
- Racial Differences in Cancer Susceptibility and Survival: More Than the Color of the Skin?Trends in cancer · 2017Review
- Merkel Cell Carcinoma of the Head in a Young African Albino Woman with HIV/HTLV-1 Coinfection Associated with Multiple Squamous Cell Carcinomas.Case reports in dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oculocutaneous albinism which is characterised by impaired melanin biosynthesis is the most common inherited pigmentary disorder of the skin and it is common among Blacks in sub-Saharan Africa. All albinos are at great risk of developing squamous cell carcinoma of sun-exposed skin, and Black albinos in sub-Saharan Africa are at about a 1000-fold higher risk of developing squamous cell carcinoma of the skin than the general population. In Black albinos, skin carcinoma tends to run an aggressive course and is likely to recur after treatment, very probably because the aetiology and predisposing factors have not changed. Prevention or reduction of occurrence of squamous cell carcinoma of the skin in Black albinos might be achieved through educating the population to increase awareness of the harmful effects of exposure to sunlight and at the same time making available effective screening programs for early detection of premalignant and malignant skin lesions in schools and communities and for early treatment.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.