Evidence map›Paper›PMID 26347739›Full record

ReviewFrontiers in immunology2015

Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014-2015.

Edward K L Chan, Jan Damoiseaux, Orlando Gabriel Carballo, Karsten Conrad, Wilson de Melo Cruvinel, Paulo Luiz Carvalho Francescantonio, Marvin J Fritzler, Ignacio Garcia-De La Torre, Manfred Herold, Tsuneyo Mimori and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 152 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
152citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

152 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  7. [Quality management in the rheumatology laboratory].Zeitschrift fur Rheumatologie · 2026
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92 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Edward K L ChanDepartment of Oral Biology, University of Florida , Gainesville, FL , USA.
Jan DamoiseauxCentral Diagnostic Laboratory, Maastricht University Medical Center , Maastricht , Netherlands.
Orlando Gabriel CarballoLaboratory of Immunology, Hospital Carlos G. Durand , Buenos Aires , Argentina ; Department of Immunology, Instituto Universitario del Hospital Italiano , Buenos Aires , Argentina.
Karsten ConradInstitute of Immunology, Technical University of Dresden , Dresden , Germany.
Wilson de Melo CruvinelPontifícia Universidade Católica de Goiás , Goiânia , Brazil.
Paulo Luiz Carvalho FrancescantonioPontifícia Universidade Católica de Goiás , Goiânia , Brazil.
Marvin J FritzlerDepartment of Medicine, Cumming School of Medicine, University of Calgary , Calgary, AB , Canada.
Ignacio Garcia-De La TorreDepartment of Immunology and Rheumatology, Hospital General de Occidente, University of Guadalajara , Guadalajara , Mexico.
Manfred HeroldDepartment of Internal Medicine VI, Medical University of Innsbruck , Innsbruck , Austria.
Tsuneyo MimoriDepartment of the Control for Rheumatic Diseases, Graduate School of Medicine, Kyoto University , Kyoto , Japan ; Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University , Kyoto , Japan.
Minoru SatohDepartment of Clinical Nursing, University of Occupational and Environmental Health , Kitakyushu , Japan.
Carlos A von MühlenBrazilian Society of Autoimmunity , Porto Alegre , Brazil.
Luis E C AndradeRheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo , São Paulo , Brazil ; Immunology Division, Fleury Medicine and Health Laboratories , São Paulo , Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the 12th International Workshop on Autoantibodies and Autoimmunity held in Sao Paulo, Brazil, on August 28, 2014, a full day session was devoted to establishing a consensus on the nomenclature of staining patterns observed in the antinuclear antibody (ANA) indirect immunofluorescence test on HEp-2 cells. The current report summarizes the collective agreements with input from the host Brazilian and international communities that represented research, clinical, and diagnostic service laboratories. Patterns are categorized in three major groups (nuclear, cytoplasmic, and mitotic patterns) and each pattern has been defined and described in detail. The consensus nomenclature and representative patterns are made available online at the international consensus on antinuclear antibody pattern (ICAP) website (www.ANApatterns.org). To facilitate continuous improvement and input, specific comments on ICAP are encouraged and these will be discussed in subsequent ICAP meetings. The ultimate goal with the establishment of the ICAP is to promote harmonization and understanding of autoantibody test nomenclature, as well as interpretation guidelines for ANA testing, thereby optimizing usage in patient care.

Indexed as

antinuclear antibodiesautoantibodyautoimmunityconsensusstandardization

Identifiers

PMID26347739
PMCPMC4542633

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.