ArticleFrontiers in immunology2015
A Microbial Feed Additive Abates Intestinal Inflammation in Atlantic Salmon.
Article in Frontiers in immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 57 citations in OpenAlex.
- Rearing system type affects baseline and post-vaccination immune gene expression in Atlantic salmon gills during smoltification.Veterinarni medicina · 2026Article
- In silico, in vitro and in vivo characterization of host-associated Latilactobacillus curvatus strains for potential probiotic applications in farmed Atlantic salmon (Salmo salar).Scientific reports · 2022Article
- Article
- Use of Probiotic Bacteria and Bacteriocins as an Alternative to Antibiotics in Aquaculture.Microorganisms · 2022Review
- Single and Multi-Strain Probiotics Supplementation in Commercially Prominent Finfish Aquaculture: Review of the Current Knowledge.Journal of microbiology and biotechnology · 2022Review
- Dietary Inclusion of Black Soldier Fly (Frontiers in immunology · 2021Article
- Review
- Nutrient Digestibility, Growth, Mucosal Barrier Status, and Activity of Leucocytes From Head Kidney of Atlantic Salmon Fed Marine- or Plant-Derived Protein and Lipid Sources.Frontiers in immunology · 2020Article
- Intestinal Transcriptome Analysis Reveals Soy Derivative-Linked Changes in Atlantic Salmon.Frontiers in immunology · 2020Article
- Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry.Scientific reports · 2019Article
- Screening of Host Specific Lactic Acid Bacteria Active AgainstFrontiers in microbiology · 2019Article
- Influence of Dietary Supplementation of ProbioticFrontiers in microbiology · 2019Article
- A New Isolate ofFrontiers in microbiology · 2019Article
- Fermented Soybean Meal Increases Lactic Acid Bacteria in Gut Microbiota of Atlantic Salmon (Salmo salar).Probiotics and antimicrobial proteins · 2018Article
- Article
- Article
- Nannochloropsis oceania-derived defatted meal as an alternative to fishmeal in Atlantic salmon feeds.PloS one · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The efficacy of a microbial feed additive (Bactocell(®)) in countering intestinal inflammation in Atlantic salmon was examined in this study. Fish were fed either the additive-coated feed (probiotic) or feed without it (control). After an initial 3-week feeding, an inflammatory condition was induced by anally intubating all the fish with oxazolone. The fish were offered the feeds for 3 more weeks. Distal intestine from the groups was obtained at 4 h, 24 h, and 3 weeks, after oxazolone treatment. Inflammatory responses were prominent in both groups at 24 h, documented by changes in intestinal micromorphology, expression of inflammation-related genes, and intestinal proteome. The control group was characterized by edema, widening of intestinal villi and lamina propria, infiltration of granulocytes and lymphocytes, and higher expression of genes related to inflammatory responses, mul1b, il1b, tnfa, ifng, compared to the probiotic group or other time points of the control group. Further, the protein expression in the probiotic group at 24 h after inducing inflammation revealed five differentially regulated proteins - Calr, Psma5, Trp1, Ctsb, and Naga. At 3 weeks after intubation, the inflammatory responses subsided in the probiotic group. The findings provide evidence that the microbial additive contributes to intestinal homeostasis in Atlantic salmon.
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Registered trials
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