Evidence map›Paper›PMID 26347512›Full record

ArticleGut and liver2016

Factors Contributing to the Preference of Korean Patients with Crohn's Disease When Selecting an Anti-Tumor Necrosis Factor Agent (CHOICE Study).

Eun Soo Kim, Kyeong Ok Kim, Byung Ik Jang, Chang Kyun Lee, Hyo Jong Kim, Kang-Moon Lee, You Sun Kim, Chang Soo Eun, Sung-Ae Jung, Suk-Kyun Yang and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Gut and liver, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. InfliximabWorld journal of gastroenterology · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Eun Soo KimDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Kyeong Ok KimDepartment of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
Byung Ik JangDepartment of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
Chang Kyun LeeDepartment of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Hyo Jong KimDepartment of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Kang-Moon LeeDepartment of Internal Medicine, The Catholic University of Korea College of Medicine, Suwon, Korea.
You Sun KimDepartment of Internal Medicine, Inje University College of Medicine, Seoul, Korea.
Chang Soo EunDepartment of Internal Medicine, Hanyang University College of Medicine, Guri, Korea.
Sung-Ae JungDepartment of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
Suk-Kyun YangDepartment of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea.
Jun LeeDepartment of Internal Medicine, Chosun University School of Medicine, Gwangju, Korea.
Tae-Oh KimDepartment of Internal Medicine, Inje University College of Medicine, Busan, Korea.
Yunho JungDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
Geom Seog SeoDepartment of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea.
Soon Man YoonDepartment of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea.
IBD Study Group of the Korean Association for the Study of the Intestinal Diseases (KASID)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsTwo comparable anti-tumor necrosis factor (TNF) agents with different routes of administration (intravenous [iv] infliximab [IFX] vs subcutaneous [sc] adalimumab [ADA]) are available for patients with Crohn's disease (CD) in Korea. This study aimed to identify the preferences of Korean CD patients for a specific anti-TNF agent and the factors contributing to the decision.

methodsA prospective survey was performed among anti-TNF-naive CD patients in 10 tertiary referral hospitals. A 16-item questionnaire addressed patient preferences and the factors contributing to the decision in favor of a particular anti-TNF agent. A logistic regression was conducted to assess predictive factors for ADA preference.

resultsOverall, 189 patients (139 males; mean age, 32.47±11.71 years) completed the questionnaire. IFX and ADA were preferred by 63.5% (120/189) and 36.5% (69/189) of patients, respectively. The most influential reason for choosing IFX was 'doctor's presence' (68.3%, 82/120), and ADA was "easy to use" (34.8%, 24/69). Amid various clinicodemographic data, having a >60-minute travel time to the hospital was a significant independent predictive factor for ADA preference.

conclusionsA large number of anti-TNF-naive Korean patients with CD preferred anti-TNFs with an iv route of administration. The reassuring effect of a doctor's presence might be the main contributing factor for this decision.

Indexed as

AdalimumabAdultAntibodies, Monoclonal, HumanizedBiological ProductsCrohn DiseaseCross-Sectional StudiesFemaleGastrointestinal AgentsHumansInfliximabInfusions, IntravenousInjections, SubcutaneousMalePatient PreferenceProspective StudiesRepublic of KoreaAdalimumabAntibodies, Monoclonal, HumanizedBiological ProductsGastrointestinal AgentsInfliximabTNF protein, humanTumor Necrosis Factor-alphaAdalimumabCrohn diseaseInfliximabPreference

Identifiers

PMID26347512
PMCPMC4849692

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.