Evidence map›Paper›PMID 26347435›Full record

ArticlePediatrics2015

Trends in Emergency Department Visits for Unsupervised Pediatric Medication Exposures, 2004-2013.

Maribeth C Lovegrove, Nina J Weidle, Daniel S Budnitz

Abstract read
In one paragraph

Article in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. US Emergency Department Visits for Antibiotic Adverse Drug Events in Children, 2019-2023.Journal of the Pediatric Infectious Diseases Society · 2026
    Article
  3. Article
  4. Patient Information Needs During Ambulatory Medication Changes: A Qualitative Study.Journal of patient-centered research and reviews · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Childhood Poisoning During the COVID-19 Pandemic.Turkish archives of pediatrics · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Parental perception of medications safe storage in the State of Qatar.Journal of family medicine and primary care · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maribeth C LovegroveDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia; mlovegrove@cdc.gov.
Nina J WeidleChenega Government Consulting, Atlanta Georgia.
Daniel S BudnitzDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia;

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundAfter reports of increasing emergency department (ED) visits for unsupervised pediatric medication exposures in the 2000s, renewed efforts to improve safety packaging and education were initiated. National data on current trends can help further target interventions.

methodsWe used nationally representative data from the National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance project (2004-2013) to assess trends in ED visits for unsupervised medication exposures in children aged <6 years. For 2010 through 2013, the dosage form and prescription status of implicated medications were identified.

resultsBased on 13,268 cases, there were an estimated 640,161 ED visits (95% confidence interval: 512,885 to 767,436) for unsupervised medication exposures from 2004 through 2013. From 2004 through 2010, ED visits for unsupervised exposures increased by an average of 5.7% annually, peaking at 75,842. After 2010, this trend reversed, and visits decreased by an average of 6.7% annually to 59,092 in 2013. From 2010 through 2013, 91.0% of unsupervised exposure visits involved 1 medication, most commonly an oral prescription solid (45.9%), oral over-the-counter (OTC) solid (22.3%), or oral OTC liquid (12.4%). More than 260 different prescription solids were implicated; opioids (13.8%) and benzodiazepines (12.7%) were the most common classes. Four medications were implicated in 91.2% of OTC liquid exposure visits: acetaminophen (32.9%), cough and cold remedies (27.5%), ibuprofen (15.7%), and diphenhydramine (15.6%).

conclusionsTargeting prevention efforts based on harm frequency and intervention feasibility can lead to continued reductions in ED visits for pediatric medication exposures.

Indexed as

AdolescentAdverse Drug Reaction Reporting SystemsChildChild, PreschoolEmergency Service, HospitalFemaleHumansInfantMalePediatricsPrescription Drug MisuseSubstance-Related DisordersUnited States

Identifiers

PMID26347435
PMCPMC4651433

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.