Evidence map›Paper›PMID 26347387›Full record

ArticleArchives of disease in childhood2015

Children with oral clefts are at greater risk for persistent low achievement in school than classmates.

George L Wehby, Brent R Collett, Sheila Barron, Paul Romitti, Timothy Ansley

Abstract read
In one paragraph

Article in Archives of disease in childhood, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. A Review and Meta-Analysis on Altered Brain Structure in Patients Born with Non-Syndromic Cleft Lip and/or Palate.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Attention Skills in Children With Nonsyndromic Cleft Lip and Palate.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Observational
  6. Article
  7. Article
  8. Mortality in Cleft Lip and Palate Patients: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Screening for Academic Risk Among Students With Cleft Lip and/or Palate: Patterns of Risk and Qualities of Effective Tools.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Gestational Age, Newborn Metabolic Markers and Academic Achievement.International journal of environmental research and public health · 2022
    Article
  17. Article
  18. Retrospective Evaluation of Number of Surgeries and Parent Ratings of Academic and Behavioral Functioning Among Children With Isolated Oral Clefts.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2021
    Article
  19. Article
  20. Brain structure and neural activity related to reading in boys with isolated oral clefts.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

George L WehbyUniversity of Iowa, Iowa City, Iowa, USA National Bureau of Economic Research, Cambridge, Massachusetts, USA.
Brent R CollettUniversity of Washington and Seattle Children's Hospital, Seattle, Washington, USA.
Sheila BarronUniversity of Iowa, Iowa City, Iowa, USA.
Paul RomittiUniversity of Iowa, Iowa City, Iowa, USA.
Timothy AnsleyUniversity of Iowa, Iowa City, Iowa, USA.

Funding

Academic achievement of children and adolescents with oral cleftsR03DE022094 · NIDCR · UNIVERSITY OF IOWA · PI WEHBY, GEORGE L · 2011 to 2012
$317k
NCBDD CDC HHS U01 DD001035NIDCR NIH HHS 1 R03 DE022094NIDCR NIH HHS R03 DE022094
6 · The paper itself

Abstract

objectivesTo examine trajectories in academic achievement for children with oral clefts versus unaffected classmates and explore predictors of persistently low achievement among children with oral clefts.

designLongitudinal cohort study of academic achievement in a population-based sample. SETTING AND

participantsChildren born from 1983 through 2003 with oral clefts were identified from the Iowa Registry for Congenital and Inherited Disorders and matched to unaffected classmates by sex, school/school district and month and year of birth.

main outcome measuresAcademic achievement was measured from Iowa Testing Programs data. Outcomes included achievement scores in reading, language and mathematics.

resultsAcademic achievement data were available for 586 children with oral clefts and 1873 unaffected classmates. Achievement trajectories were stable for both groups. Children with oral clefts were more likely than their classmates to be classified into persistent low achievement trajectories, including when adjusting for socioeconomic differences: OR=1.63, 95% CI 1.23 to 2.16 for reading; OR=1.73, 95% CI 1.29 to 2.31 for language; OR=1.45, 95% CI 1.05 to 1.99 for math. Predictors of low achievement were cleft palate only (vs other cleft types), adolescent mothers, low maternal education and less frequent use of prenatal care.

conclusionsMost children have steady academic trajectories and children with oral clefts are at greater risk for persistent low achievement in school than unaffected classmates. These findings support the need for routine, early screening for academic deficits in this population. Cleft palate only, low parental education and adolescent mothers are associated with increased risk for persistent low achievement.

Indexed as

AchievementAdolescentChildCleft LipCleft PalateCohort StudiesEducational MeasurementFemaleHumansLearning DisabilitiesLongitudinal StudiesMaleMothersRiskSchoolsStudentsBirth DefectsChild PsychologyCleft LipCleft PalateSchool Health

Identifiers

PMID26347387
PMCPMC5018039

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.