Evidence map›Paper›PMID 26347247›Full record

ArticleEuropean journal of nutrition2016

Fatty acid composition in breastfeeding and school performance in children aged 12 years.

Geertje W Dalmeijer, Alet H Wijga, Ulrike Gehring, Carry M Renders, Gerard H Koppelman, Henriette A Smit, Lenie van Rossem

Open access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Geertje W DalmeijerJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, STR 6.131, PO Box 85500, 3508GA, Utrecht, The Netherlands.
Alet H WijgaNational Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Ulrike GehringInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Carry M RendersDepartment of Health Sciences, Faculty of Earth and Life Sciences, and EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands.
Gerard H KoppelmanDepartment of Pediatric Pulmonology and Pediatric Allergology, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, and Beatrix Children's Hospital, University of Groningen, Groningen, The Netherlands.
Henriette A SmitJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, STR 6.131, PO Box 85500, 3508GA, Utrecht, The Netherlands.
Lenie van RossemJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, STR 6.131, PO Box 85500, 3508GA, Utrecht, The Netherlands. L.vanRossem@umcutrecht.nl.ORCID http://orcid.org/0000-0002-0405-4781
Utrecht University · NLAmsterdam Public Health · NLNational Institute for Public Health and the Environment · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBreastfeeding has been associated with improved cognition. It remains unclear whether long-chain polyunsaturated fatty acids (LC-PUFAs) play a role in this association. We assessed the association between LC-PUFA concentrations in infant feeding and school performance at age 12.

methodsWithin a population-based birth cohort, we compared school performance of 277 non-breastfed children and 157 children who had fatty acid composition of their mothers' breast milk measured. Two indicators of school performance were: (1) the score on a standardized achievement test and (2) the teacher's advice regarding a child's potential performance level in secondary education. Linear regression and multinomial logistic regression analyses were performed to assess the independent association between LC-PUFA content of breast milk and school performance.

resultsGirls, who received breast milk with a relative high content (above the median) of docosahexaenoic acid (DHA), had a higher Cito-test score (β = 2.96 points, 95 % CI 0.24; 5.69) than non-breastfed girls. Among the breastfed girls, each percentage point of higher content of total n-3 LC-PUFA (β = 4.55, 95 % CI 0.43; 8.66) and DHA (β = 7.09, 95 % CI 0.9; 13.3) was associated with a higher Cito-test score. The association between LC-PUFA content and teacher school advice showed a similar pattern. There was no association between LC-PUFA content and school performance in boys.

conclusionAlthough a large part of the association between infant milk feeding and cognition seems to be explained by sociodemographic and lifestyle-related factors, a relative high content of n-3 PUFAs, especially DHA, in breast milk is associated with better school performance in 12-year-old girls but not in boys.

Indexed as

CognitionAchievementChildDocosahexaenoic AcidsFatty Acids, Omega-3FemaleHumansInfantInfant FormulaInfant Nutritional Physiological PhenomenaLinear ModelsMaleMilk, HumanProspective StudiesDocosahexaenoic AcidsFatty Acids, Omega-3Birth cohortBreastfeedingFatty acid compositionSchool performance

Identifiers

PMID26347247
PMCPMC5035317
OpenAlexW1754678989

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.