Evidence map›Paper›PMID 26347203›Full record

ReviewJournal of diabetes research2015

Roles of Commensal Microbiota in Pancreas Homeostasis and Pancreatic Pathologies.

Camila Leal-Lopes, Fernando J Velloso, Julia C Campopiano, Mari C Sogayar, Ricardo G Correa

Abstract readReview
In one paragraph

Review in Journal of diabetes research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Iranian journal of microbiology · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Fungi, host immune response, and tumorigenesis.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Review
  8. Review
  9. Article
  10. State of the Art in Exocrine Pancreatic Insufficiency.Medicina (Kaunas, Lithuania) · 2020
    Review
  11. Review
  12. Microbes and Cancer: Friends or Faux?International journal of molecular sciences · 2020
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Microorganisms · 2018
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Camila Leal-LopesDepartment of Biochemistry, Chemistry Institute, University of São Paulo, 05508-000 São Paulo, SP, Brazil ; Cell and Molecular Therapy Center (NUCEL-NETCEM), School of Medicine, University of São Paulo, 05360-130 São Paulo, SP, Brazil.
Fernando J VellosoCell and Molecular Therapy Center (NUCEL-NETCEM), School of Medicine, University of São Paulo, 05360-130 São Paulo, SP, Brazil.
Julia C CampopianoCell and Molecular Therapy Center (NUCEL-NETCEM), School of Medicine, University of São Paulo, 05360-130 São Paulo, SP, Brazil.
Mari C SogayarDepartment of Biochemistry, Chemistry Institute, University of São Paulo, 05508-000 São Paulo, SP, Brazil ; Cell and Molecular Therapy Center (NUCEL-NETCEM), School of Medicine, University of São Paulo, 05360-130 São Paulo, SP, Brazil.
Ricardo G CorreaSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pancreas plays a central role in metabolism, allowing ingested food to be converted and used as fuel by the cells throughout the body. On the other hand, the pancreas may be affected by devastating diseases, such as pancreatitis, pancreatic adenocarcinoma (PAC), and diabetes mellitus (DM), which generally results in a wide metabolic imbalance. The causes for the development and progression of these diseases are still controversial; therefore it is essential to better understand the underlying mechanisms which compromise the pancreatic homeostasis. The interest in the study of the commensal microbiome increased extensively in recent years, when many discoveries have illustrated its central role in both human physiology and maintenance of homeostasis. Further understanding of the involvement of the microbiome during the development of pathological conditions is critical for the improvement of new diagnostic and therapeutic approaches. In the present review, we discuss recent findings on the behavior and functions played by the microbiota in major pancreatic diseases and provide further insights into its potential roles in the maintenance of pancreatic steady-state activities.

Indexed as

Gastrointestinal MicrobiomeAnimalsDiabetes ComplicationsDiabetes MellitusDisease ProgressionHomeostasisHumansInflammationPancreasPancreatic NeoplasmsPancreatitisPatient Safety

Identifiers

PMID26347203
PMCPMC4544440

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.