ReviewMediators of inflammation2015
Periodontal Diseases and Dental Caries in Children with Type 1 Diabetes Mellitus.
Review in Mediators of inflammation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06924372 (Application of Salivary Biomarkers in Risk Assessment for Oral Diseases in Children With Type 1 Diabetes), which is not on this map. Cited by 38 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Application of Salivary Biomarkers in Risk Assessment for Oral Diseases in Children With Type 1 Diabetes
Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Early childhood caries and type 1 diabetes mellitus - Evidence on primary teeth and oral health: A systematic review.Biomolecules & biomedicine · 2026Pooled it
- Poor glycemic control impairs oral health in children with type 1 diabetes mellitus - a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Prevalence of dental caries in children and adolescents with type 1 diabetes: a systematic review and meta-analysis.BMC oral health · 2019Pooled it
- Association between miR-21 polymorphism and the risk of primary dental caries in preschool children.Odontology · 2026Article
- Oral health and salivary inflammatory markers in children and adolescents with type 1 diabetes: A cross-sectional study.Journal of endocrinological investigation · 2026Article
- Oral health status and preventive determinants in children with type 1 diabetes: a cross-sectional comparative study.Frontiers in dental medicine · 2026Article
- Clinical studies on the effect of type 1 diabetes on oral health in children and adolescents aged 6-17 years. A literature review.Medicine and pharmacy reports · 2026Review
- Bridging oral and systemic health: exploring pathogenesis, biomarkers, and diagnostic innovations in periodontal disease.Infection · 2025Review
- Oral Health-Related Quality of Life, Behaviours and Oral Manifestations in a Paediatric Population with Type I Diabetes Mellitus: A Comparative Cross-Sectional Study.Dentistry journal · 2025Article
- Management of Dental Demineralization in a Patient with Complex Medical Conditions: A Case Report and Clinical Outcomes.Reports (MDPI) · 2025Article
- Article
- Oral Health of Children and Adolescents with Diabetes Mellitus.Journal of clinical medicine · 2024Article
- Prevalence and Severity of Periodontal Disease in Diabetic Patients in South Jordan: A Cross-Sectional Study.Cureus · 2024Article
- Dental health status of children with diabetes in Riyadh, Saudi Arabia.The Saudi dental journal · 2024Article
- Predicting Teeth Extraction after Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Cancer Patients Using the Novel GLUCAR Index.Diagnostics (Basel, Switzerland) · 2023Article
- Prediction model of dental caries in 12-year-old children in Sichuan Province based on machine learning.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2023Article
- Periodontal Disease and Its Association with Metabolic Syndrome-A Comprehensive Review.International journal of molecular sciences · 2023Review
- Studying ancient human oral microbiomes could yield insights into the evolutionary history of noncommunicable diseases.F1000Research · 2023Review
- Type 1 diabetes, glycemic traits, and risk of dental caries: a Mendelian randomization study.Frontiers in genetics · 2023Article
- Discovering genetic linkage between periodontitis and type 1 diabetes: A bioinformatics study.Frontiers in genetics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type 1 diabetes mellitus is a chronic metabolic disease of an autoimmune origin with early manifestation predominantly in the childhood. Its incidence has been rising in most European countries. Diabetes has been intensively studied by all branches of medicine. There were a number of studies investigating oral consequences of diabetes; however, unambiguous conclusions were drawn only for the relationship between diabetes and periodontal impairment. Many studies confirmed higher plaque levels and higher incidence of chronic gingivitis both in adults and in children with diabetes. Juvenile periodontitis is rare both in healthy subjects and in those with type 1 diabetes. Yet certain findings from well-conducted studies, for example, differences in oral microflora or the impact of metabolic control of diabetes on periodontal health, indicate a higher risk of periodontitis in children with type 1 diabetes. As for the association of diabetes and dental caries, the results of the studies are inconsistent. However, it was found that some risk factors for dental caries are either more or less prevalent in the diabetic population. Despite an extensive research in this area we have to acknowledge that many questions have remained unanswered. There is a need for continued, thorough research in this area.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.