Evidence map›Paper›PMID 26346969›Full record

ArticleScientific reports2015

Polymeric and Solid Lipid Nanoparticles for Sustained Release of Carbendazim and Tebuconazole in Agricultural Applications.

Estefânia Vangelie Ramos Campos, Jhones Luiz de Oliveira, Camila Morais Gonçalves da Silva, Mônica Pascoli, Tatiane Pasquoto, Renata Lima, P C Abhilash, Leonardo Fernandes Fraceto

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 204 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Microbial Nanoparticles in Biological Plant Protection.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Toxics · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. Chitosan Nanoparticles as Oral Drug Carriers.International journal of molecular sciences · 2023
    Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Estefânia Vangelie Ramos CamposDepartment of Environmental Engineering, State University of São Paulo (UNESP), Sorocaba, SP, Brazil.
Jhones Luiz de OliveiraDepartment of Environmental Engineering, State University of São Paulo (UNESP), Sorocaba, SP, Brazil.
Camila Morais Gonçalves da SilvaDepartment of Biochemistry, Institute of Biology, State University of Campinas (UNICAMP), Cidade Universitária Zeferino Vaz, Campinas, SP, Brazil.
Mônica PascoliDepartment of Biotechnology, University of Sorocaba, Sorocaba, SP, Brazil.
Tatiane PasquotoDepartment of Biotechnology, University of Sorocaba, Sorocaba, SP, Brazil.
Renata LimaDepartment of Biotechnology, University of Sorocaba, Sorocaba, SP, Brazil.
P C AbhilashInstitute of Environment &Sustainable Development, Banaras Hindu University, Varanasi, India.
Leonardo Fernandes FracetoDepartment of Environmental Engineering, State University of São Paulo (UNESP), Sorocaba, SP, Brazil.
Universidade de Sorocaba · BRUniversidade de São Paulo · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbendazim (MBC) (methyl-2-benzimidazole carbamate) and tebuconazole (TBZ) ((RS)-1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol) are widely used in agriculture for the prevention and control of fungal diseases. Solid lipid nanoparticles and polymeric nanocapsules are carrier systems that offer advantages including changes in the release profiles of bioactive compounds and their transfer to the site of action, reduced losses due to leaching or degradation, and decreased toxicity in the environment and humans. The objective of this study was to prepare these two types of nanoparticle as carrier systems for a combination of TBZ and MBC, and then investigate the release profiles of the fungicides as well as the stabilities and cytotoxicities of the formulations. Both nanoparticle systems presented high association efficiency (>99%), indicating good interaction between the fungicides and the nanoparticles. The release profiles of MBC and TBZ were modified when the compounds were loaded in the nanoparticles, and cytotoxicity assays showed that encapsulation of the fungicides decreased their toxicity. These fungicide systems offer new options for the treatment and prevention of fungal diseases in plants.

Indexed as

AgricultureDelayed-Action PreparationsLipidsNanoparticlesPolymersBenzimidazolesCarbamatesChemistry, PharmaceuticalDrug StabilityFungicides, IndustrialModels, TheoreticalNanocapsulesParticle SizeTriazolesBenzimidazolesCarbamatescarbendazimDelayed-Action PreparationsFungicides, IndustrialLipidsNanocapsulesPolymerstebuconazoleTriazoles

Identifiers

PMID26346969
PMCPMC4561881
OpenAlexW1457890428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.