ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2015
Comparison of a distal end-to-side neurorrhaphy with a proximal-distal end-to-side neurorrhaphy: in a rat model.
Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Gunshot and blast injuries of the extremities: a review of 45 cases.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2019Pooled it
- Experimental study on the repair of peripheral nerve injuriesFrontiers in neurology · 2023Article
- Current concepts in peripheral nerve surgery.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeripheral nerve injuries have severe consequences on quality of life, especially in cases with extensive or old injuries when standard nerve repair is impossible and proposed repair methods are not completely satisfactory. Terminolateral neurorrhaphy is a practical and advantageous technique for nerve repair; therefore, we developed a nerve function study to evaluate advantages of proximal stump coaptation in end-to-side nerve repair method.
methodsThree experimental groups were studied: In group A, the proximal and distal stumps of the transected peroneal nerve were sutured to the posterior tibialis nerve in left side and right side left intact; in group B, a classic end-to-side neurorrhaphy was performed; and group C was without neurorrhaphy as the control group. Five months later, visual functional assessment of sciatic nerves was performed to assess the statistic sciatic index (SSI).
resultsThe surgical procedures caused an ipsilateral rehabilitation in groups A and B compared with the control group (p < 0.05). Although comparison of intermediate toe spread factor of distal-proximal nerve repair and distal nerve repair (DNR) was not statistically significant, toe spread factor and subsequently SSI comparisons showed significant statistical difference (p < 0.05). DISCUSSION: Contribution of proximal nerve stump to DNR improved functional recovery of motor neurons in an end-to-side cooptation method in rat lower extremity. Some of possible explanations for positive results could be the presence of more neuroattractive substances and use of donor nerve epineurium as a neuropermissive bridge for the regenerated axons.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.