Evidence map›Paper›PMID 26346739›Full record

ReviewInternational journal of inflammation2015

Deciphering Asthma Biomarkers with Protein Profiling Technology.

Zhizhou Kuang, Jarad J Wilson, Shuhong Luo, Si-Wei Zhu, Ruo-Pan Huang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of inflammation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Biomarkers for selecting biologic therapies in asthma.Therapeutic advances in respiratory disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Zhizhou KuangRayBiotech, Inc., Guangzhou 510600, China ; RayBiotech, Inc., 3607 Parkway Lane, Norcross, GA 30092, USA ; South China Biochip Research Center, Guangzhou 510600, China.
Jarad J WilsonRayBiotech, Inc., 3607 Parkway Lane, Norcross, GA 30092, USA.
Shuhong LuoRayBiotech, Inc., Guangzhou 510600, China ; RayBiotech, Inc., 3607 Parkway Lane, Norcross, GA 30092, USA ; South China Biochip Research Center, Guangzhou 510600, China.
Si-Wei ZhuRayBiotech, Inc., Guangzhou 510600, China.
Ruo-Pan HuangRayBiotech, Inc., Guangzhou 510600, China ; RayBiotech, Inc., 3607 Parkway Lane, Norcross, GA 30092, USA ; South China Biochip Research Center, Guangzhou 510600, China.
RayBiotech (China) · CNRayBiotech (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a chronic inflammatory disease of the airways, resulting in bronchial hyperresponsiveness with every allergen exposure. It is now clear that asthma is not a single disease, but rather a multifaceted syndrome that results from a variety of biologic mechanisms. Asthma is further problematic given that the disease consists of many variants, each with its own etiologic and pathophysiologic factors, including different cellular responses and inflammatory phenotypes. These facets make the rapid and accurate diagnosis (not to mention treatments) of asthma extremely difficult. Protein biomarkers can serve as powerful detection tools in both clinical and basic research applications. Recent endeavors from biomedical researchers have developed technical platforms, such as cytokine antibody arrays, that have been employed and used to further the global analysis of asthma biomarker studies. In this review, we discuss potential asthma biomarkers involved in the pathophysiologic process and eventual pathogenesis of asthma, how these biomarkers are being utilized, and how further testing methods might help improve the diagnosis and treatment strain that current asthma patients suffer.

Identifiers

PMID26346739
PMCPMC4543788
OpenAlexW1558714858

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.