Evidence map›Paper›PMID 26346700›Full record

ReviewJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2015

Fractal frontiers in cardiovascular magnetic resonance: towards clinical implementation.

Gabriella Captur, Audrey L Karperien, Chunming Li, Filip Zemrak, Catalina Tobon-Gomez, Xuexin Gao, David A Bluemke, Perry M Elliott, Steffen E Petersen, James C Moon

Abstract readReview
In one paragraph

Review in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Society for Cardiovascular Magnetic Resonance reference values ("normal values") in cardiovascular magnetic resonance: 2025 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Guideline
  2. Article
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  11. Left ventricular noncompaction in pediatric population: could cardiovascular magnetic resonance derived fractal analysis aid diagnosis?Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  12. Article
  13. Reference ranges ("normal values") for cardiovascular magnetic resonance (CMR) in adults and children: 2020 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Review
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gabriella CapturUCL Institute of Cardiovascular Science, University College London, Gower Street, London, WC1E 6BT, UK. gabriella.captur.11@ucl.ac.uk.
Audrey L KarperienCentre for Research in Complex Systems, School of Community Health, Charles Sturt University, Albury, NSW 2640, Australia. akarperien@yahoo.com.
Chunming LiDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, USA. li_chunming@hotmail.com.
Filip ZemrakDivision of Cardiovascular Imaging, The Heart Hospital, part of University College London NHS Foundation Trust, 16-18 Westmoreland Street, London, W1G 8PH, UK. filip.zemrak@gmail.com.
Catalina Tobon-GomezDivision of Imaging Sciences & Biomedical Engineering, King's College London, London, UK. catactg@gmail.com.
Xuexin GaoCircle Cardiovascular Imaging Inc., Panarctic Plaza, Suite 250, 815 8th Avenue SW, Calgary, AB T2P 3P2, Canada. gavin@circlecvi.com.
David A BluemkeRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Center Drive, Bethesda, MA, USA. bluemked@cc.nih.gov.
Perry M ElliottUCL Institute of Cardiovascular Science, University College London, Gower Street, London, WC1E 6BT, UK. perry.elliott@ucl.ac.uk.
Steffen E PetersenDivision of Cardiovascular Imaging, The Heart Hospital, part of University College London NHS Foundation Trust, 16-18 Westmoreland Street, London, W1G 8PH, UK. s.e.petersen@qmul.ac.uk.
James C MoonUCL Institute of Cardiovascular Science, University College London, Gower Street, London, WC1E 6BT, UK. j.moon@ucl.ac.uk.

Funding

Molecular Biomedical Imaging Laboratory (NIBIB)ZIAEB000072 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI BLUEMKE, DAVID · 2010 to 2017
$5.0M
Molecular Biomedical Imaging Laboratory (CC)ZIACL090019 · CLC · CLINICAL CENTER · PI JONES, ELIZABETH C. · 2010 to 2017
$0k
British Heart Foundation FS/10/40/28260British Heart Foundation FS/12/56/29723Intramural NIH HHS
6 · The paper itself

Abstract

Many of the structures and parameters that are detected, measured and reported in cardiovascular magnetic resonance (CMR) have at least some properties that are fractal, meaning complex and self-similar at different scales. To date however, there has been little use of fractal geometry in CMR; by comparison, many more applications of fractal analysis have been published in MR imaging of the brain.This review explains the fundamental principles of fractal geometry, places the fractal dimension into a meaningful context within the realms of Euclidean and topological space, and defines its role in digital image processing. It summarises the basic mathematics, highlights strengths and potential limitations of its application to biomedical imaging, shows key current examples and suggests a simple route for its successful clinical implementation by the CMR community.By simplifying some of the more abstract concepts of deterministic fractals, this review invites CMR scientists (clinicians, technologists, physicists) to experiment with fractal analysis as a means of developing the next generation of intelligent quantitative cardiac imaging tools.

Indexed as

Cardiovascular SystemFractalsModels, CardiovascularAnimalsCardiovascular DiseasesHumansImage Interpretation, Computer-AssistedMagnetic Resonance Imaging, CinePredictive Value of TestsPrognosis

Identifiers

PMID26346700
PMCPMC4562373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.