Evidence map›Paper›PMID 26346216›Full record

ArticleMediators of inflammation2015

C-Reactive Protein in Peripheral Blood of Patients with Chronic and Aggressive Periodontitis, Gingivitis, and Gingival Recessions.

Stepan Podzimek, Jaroslav Mysak, Tatjana Janatova, Jana Duskova

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Review
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  8. Observational
  9. Article
  10. Association between periodontitis and serum c-reactive protein levels.Journal of clinical and experimental dentistry · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Risk factors and outcomes of acute renal infarction.Kidney research and clinical practice · 2016
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stepan PodzimekSchool of Dental Medicine, First Faculty of Medicine and General University Hospital, Charles University, Karlovo Náměstí 32, Katerinska 32, 121 11 Prague, Czech Republic.
Jaroslav MysakSchool of Dental Medicine, First Faculty of Medicine and General University Hospital, Charles University, Karlovo Náměstí 32, Katerinska 32, 121 11 Prague, Czech Republic.
Tatjana JanatovaSchool of Dental Medicine, First Faculty of Medicine and General University Hospital, Charles University, Karlovo Náměstí 32, Katerinska 32, 121 11 Prague, Czech Republic.
Jana DuskovaSchool of Dental Medicine, First Faculty of Medicine and General University Hospital, Charles University, Karlovo Náměstí 32, Katerinska 32, 121 11 Prague, Czech Republic.
Charles University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CRP is a plasma protein that reflects a measure of the acute phase response to inflammation and is one of the markers of choice in monitoring this response. CRP can be used for the prediction and early detection of periodontal disease. The aim of this study was to compare and evaluate the systemic levels of CRP in the peripheral blood samples of patients with chronic and aggressive periodontitis, gingivitis, and gingival recessions and compare them with periodontal clinical parameters. All patients (N = 158) were examined prior to the initiation of periodontal treatment. Patients were divided into four groups. Group A consisted of 26 patients with aggressive periodontitis, Group B consisted of 111 patients with chronic periodontitis, Group C consisted of 13 patients with gingivitis, and Group D consisted of 8 patients with gingival recessions. Our study results indicate that CRP levels increase subsequently with the severity of the periodontal disease and that the bleeding on probing index showed much better positive correlation with the CRP levels compared to the pocket depth index in both periodontitis patients groups, especially in aggressive periodontitis patients.

Indexed as

AdultAggressive PeriodontitisChronic PeriodontitisC-Reactive ProteinFemaleGingival RecessionGingivitisHumansMaleMiddle AgedC-Reactive Protein

Identifiers

PMID26346216
PMCPMC4539496
OpenAlexW1599749832

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.