ArticleThe International journal on drug policy2016
Prescription monitoring programs and emergency department visits involving benzodiazepine misuse: Early evidence from 11 United States metropolitan areas.
Article in The International journal on drug policy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Association Between Prescription Drug Monitoring Programs and Nonfatal and Fatal Drug Overdoses: A Systematic Review.Annals of internal medicine · 2018Pooled it
- Reducing prescribing of benzodiazepines in older adults: a comparison of four physician-focused interventions by a medical regulatory authority.BMC family practice · 2021Trial
- Assessment of beliefs and attitudes towards benzodiazepines using machine learning based on social media posts: an observational study.BMC psychiatry · 2024Observational
- Black-Box Warnings of Antiseizure Medications: What is Inside the Box?Pharmaceutical medicine · 2023Review
- Systematic Identification and Categorization of Opioid Prescribing and Dispensing Policies in 16 States and Washington, DC.Pain medicine (Malden, Mass.) · 2023Article
- Benzodiazepines: Uses, Dangers, and Clinical Considerations.Neurology international · 2021Review
- Prescription Opioid Laws and Opioid Dispensing in US Counties: Identifying Salient Law Provisions With Machine Learning.Epidemiology (Cambridge, Mass.) · 2021Article
- Mandatory use of prescription drug monitoring program and benzodiazepine prescribing among U.S. Medicaid enrollees.Substance abuse · 2021Article
- Beyond Prescriptions Monitoring Programs: The Importance of Having the Conversation about Benzodiazepine Use.Journal of clinical medicine · 2019Article
- Prescription drug monitoring programs and drug overdose deaths involving benzodiazepines and prescription opioids.Drug and alcohol review · 2019Article
- Prescription Drug Monitoring Programs and Opioid Overdoses: Exploring Sources of Heterogeneity.Epidemiology (Cambridge, Mass.) · 2019Article
- Factors associated with sedative use and misuse among heroin users.Drug and alcohol dependence · 2018Article
- Ketamine and Beyond: Investigations into the Potential of Glutamatergic Agents to Treat Depression.Drugs · 2017Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundEmergency department (ED) visits involving benzodiazepines have increased in the United States. Most states have created prescription monitoring programs (PMPs) to improve drug prescribing safety. To determine the association between PMP implementation and ED visits involving benzodiazepine misuse, we conducted a retrospective analysis of data from 11 metropolitan areas in the United States from 2004 to 2011.
methodsWe estimated rates of ED visits per 100,000 residents involving benzodiazepine misuse from the Drug Abuse Warning Network dataset. Dates of PMP implementation were obtained from program administrators. We used linear regression models to assess whether PMP implementation was associated with a change in ED visits involving benzodiazepines. Models were adjusted for calendar quarter, metropolitan area, and metropolitan area-specific linear time trends.
resultsRates of ED visits involving benzodiazepine misuse increased in all metropolitan areas during the study period. PMP implementation was not associated with a change in ED visits (mean difference: 0.9 [95% CI: -0.09 to 1.9] visits per 100,000 population per quarter; p=0.08). When analyzed by number of years after implementation, PMPs were associated with a higher visit rate in year one (0.8 [95% CI: 0.2-1.5]; p=0.01]), but not in year two (0.3 [95% CI: -2.1-2.8]; p=0.78) or year three or later (2.1 [95% CI: -0.4-4.7]; p=0.10).
conclusionWe did not find evidence that PMP implementation was associated with reductions in ED visits involving benzodiazepine misuse. Future work should identify PMP features and capabilities that improve benzodiazepine safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.