ArticleScientific reports2015
Very low embryonic crude oil exposures cause lasting cardiac defects in salmon and herring.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 167 citations in OpenAlex.
- Subchronic PAH Exposure Impacts Cardiac Electrophysiology of the Polar Fish, Navaga Cod (Toxics · 2026Article
- Biological Responses of Pacific Herring Embryos to Crude Oil Are Quantifiable at Exposure Levels Below Conventional Limits of Quantitation for PAHs in Water and Tissues.Environmental science & technology · 2023Article
- Recommendations for advancing media preparation methods used to assess aquatic hazards of oils and spill response agents.Aquatic toxicology (Amsterdam, Netherlands) · 2023Review
- Acute and Chronic Effects of Crude Oil Water-Accommodated Fractions on the Early Life Stages of Marine Medaka (Toxics · 2023Article
- Smaller herring larval size-at-stage in response to environmental changes is associated with ontogenic processes and stress response.Conservation physiology · 2023Article
- Fathead Minnows Exposed to Organic Compounds from Oil Sands Tailings as Embryos Have Reduced Survival, Impaired Development, and Altered Behaviors That Persist into Larval Stages.Environmental toxicology and chemistry · 2022Article
- A review of the toxicology of oil in vertebrates: what we have learned following theJournal of toxicology and environmental health. Part B, Critical reviews · 2021Review
- Pro-oxidant potency of clothianidin in rainbow trout.Arhiv za higijenu rada i toksikologiju · 2021Article
- Combined effects of crude oil exposure and warming on eggs and larvae of an arctic forage fish.Scientific reports · 2021Article
- Brazilian silverside,PeerJ · 2021Article
- Effects of Exposure to Low Concentrations of Oil on the Expression of Cytochrome P4501a and Routine Swimming Speed of Atlantic Haddock (Environmental science & technology · 2020Article
- Long-Term Ecological Impacts from Oil Spills: Comparison ofEnvironmental science & technology · 2020Article
- Article
- Embryonic Crude Oil Exposure Impairs Growth and Lipid Allocation in a Keystone Arctic Forage Fish.iScience · 2019Article
- Chronic toxicity of oil sands tailings pond sediments to early life stages of fathead minnow (Heliyon · 2019Article
- Applying spatiotemporal models to monitoring data to quantify fish population responses to the Deepwater Horizon oil spill in the Gulf of Mexico.Environmental monitoring and assessment · 2018Article
- Herring supports Northeast Pacific predators and fisheries: Insights from ecosystem modelling and management strategy evaluation.PloS one · 2018Article
- Article
- The Development of Long-Term Adverse Health Effects in Oil Spill Cleanup Workers of the Deepwater Horizon Offshore Drilling Rig Disaster.Frontiers in public health · 2018Article
- Later life swimming performance and persistent heart damage following subteratogenic PAH mixture exposure in the Atlantic killifish (Fundulus heteroclitus).Environmental toxicology and chemistry · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 1989 Exxon Valdez disaster exposed embryos of pink salmon and Pacific herring to crude oil in shoreline spawning habitats throughout Prince William Sound, Alaska. The herring fishery collapsed four years later. The role of the spill, if any, in this decline remains one of the most controversial unanswered questions in modern natural resource injury assessment. Crude oil disrupts excitation-contraction coupling in fish heart muscle cells, and we show here that salmon and herring exposed as embryos to trace levels of crude oil grow into juveniles with abnormal hearts and reduced cardiorespiratory function, the latter a key determinant of individual survival and population recruitment. Oil exposure during cardiogenesis led to specific defects in the outflow tract and compact myocardium, and a hypertrophic response in spongy myocardium, evident in juveniles 7 to 9 months after exposure. The thresholds for developmental cardiotoxicity were remarkably low, suggesting the scale of the Exxon Valdez impact in shoreline spawning habitats was much greater than previously appreciated. Moreover, an irreversible loss of cardiac fitness and consequent increases in delayed mortality in oil-exposed cohorts may have been important contributors to the delayed decline of pink salmon and herring stocks in Prince William Sound.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.