ArticlePLoS currents2015
Novel Human-like Influenza A Viruses Circulate in Swine in Mexico and Chile.
Article in PLoS currents, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Epidemiological features of influenza circulation in swine populations: A systematic review and meta-analysis.PloS one · 2017Pooled it
- Review
- Replication kinetics of novel swine influenza A viruses: an approach to vaccine production.Austral journal of veterinary sciences · 2024Article
- Novel influenza A viruses in pigs with zoonotic potential, Chile.Microbiology spectrum · 2024Article
- Novel introductions of human-origin H3N2 influenza viruses in swine, Chile.Frontiers in veterinary science · 2024Article
- Cross-protection of commercial vaccines against Chilean swine influenza A virus using the guinea pig model as a surrogate.Frontiers in veterinary science · 2023Article
- Human-to-swine introductions and onward transmission of 2009 H1N1 pandemic influenza viruses in Brazil.Frontiers in microbiology · 2023Article
- Evidence of influenza A infection and risk of transmission between pigs and farmworkers.Zoonoses and public health · 2022Article
- Antigenic characterization of influenza and SARS-CoV-2 viruses.Analytical and bioanalytical chemistry · 2022Review
- Zooming in on the molecular characteristics of swine influenza virus circulating in Colombia before and after the H1N1pdm09 virus.Frontiers in veterinary science · 2022Article
- Ubiquitous influenza A virus in Chilean swine before the H1N1pdm09 introduction.Transboundary and emerging diseases · 2021Article
- Swine Influenza A Viruses and the Tangled Relationship with Humans.Cold Spring Harbor perspectives in medicine · 2021Review
- Risk factors and spatial relative risk assessment for influenza A virus in poultry and swine in backyard production systems of central Chile.Veterinary medicine and science · 2020Article
- When Pigs Fly: Pandemic influenza enters the 21st century.PLoS pathogens · 2020Review
- Influenza A Virus in Swine: Epidemiology, Challenges and Vaccination Strategies.Frontiers in veterinary science · 2020Review
- Human-Origin Influenza A(H3N2) Reassortant Viruses in Swine, Southeast Mexico.Emerging infectious diseases · 2019Article
- Infection of novel reassortant H1N2 and H3N2 swine influenza A viruses in the guinea pig model.Veterinary research · 2018Article
- Adaptation of Human Influenza Viruses to Swine.Frontiers in veterinary science · 2018Review
- Influenza A virus vaccines for swine.Veterinary microbiology · 2017Article
- Swine Influenza Virus (H1N2) Characterization and Transmission in Ferrets, Chile.Emerging infectious diseases · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFurther understanding of the genetic diversity and evolution of influenza A viruses circulating in swine (IAV-S) is important for the development of effective vaccines and our knowledge of pandemic threats. Until recently, very little was known of IAV-S diversity in Latin America, owing to a lack of surveillance.
methodsTo address this gap, we sequenced and conducted a phylogenetic analysis of 69 hemagglutinin (HA) sequences from IAV-S isolates collected in swine in Mexico and Chile during 2010-2014, including the H1N1, H1N2, and H3N2 subtypes.
resultsOur analysis identified multiple IAV-S lineages that appear to have been circulating undetected in swine for decades, including four novel IAV-S lineages of human seasonal virus origin that have not been previously identified in any swine populations globally. We also found evidence of repeated introductions of pandemic H1N1 viruses from humans into swine in Mexico and Chile since 2009, and incursions of H1 and H3 viruses from North American swine into Mexico. DISCUSSION: Overall, our findings indicate that at least 12 genetically distinct HA lineages circulate in Latin American swine herds, only two of which have been found in North American swine herds. Human-to-swine transmission, spatial migration via swine movements, and genomic reassortment are the key evolutionary mechanisms that generate this viral diversity. Additional antigenic characterization and whole-genome sequencing is greatly needed to understand the diversity and independent evolution of IAV-S in Latin America.
Identifiers
26345598PMC4551470W2398130458What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.