ReviewClinical, cosmetic and investigational dentistry2015
Pediatric dental sedation: challenges and opportunities.
Review in Clinical, cosmetic and investigational dentistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Non-pharmacological interventions for reducing dental anxiety in pediatric dentistry: a network meta-analysis.BMC oral health · 2024Pooled it
- Systematic review and meta-analysis comparing the efficacy of dexmedetomidine to midazolam as premedication and a sedative agent in pediatric patients undergoing dental procedures.Oral and maxillofacial surgery · 2023Pooled it
- A Prospective Randomized Controlled Trial Using Virtual Reality in Pediatric Pre-intervention Echocardiograms to Decrease Child Anxiety and Fear.Pediatric cardiology · 2025Trial
- The effect of dexmedetomidine-ketamine combination versus dexmedetomidine on behavior of uncooperative pediatric dental patients: a randomized controlled clinical trial.Journal of applied oral science : revista FOB · 2024Trial
- Safety, Pharmacokinetics, and Pharmacodynamics of Midazolam Gel After Rectal Administration in Healthy Chinese Subjects.Clinical drug investigation · 2023Trial
- Association between body mass index z-score and hypoxemia during pediatric dental sedation: a retrospective cohort study.Journal of anesthesia · 2026Article
- Efficacy and Safety of Nitrous Oxide and Midazolam Sedation Protocols in Pediatric Dentistry: A Multicenter Clinical Retrospective Study.Children (Basel, Switzerland) · 2026Article
- Comparison of Parental Perceptions and Oxygen Saturation Response to Papoose Board and Comfy Wrap Restraints in Pediatric Dental Procedures: A Crossover Study.International journal of clinical pediatric dentistry · 2026Article
- Sedation and General Anesthesia in Non-Cooperative Dental Patients: An Italian Clinical Experience.Journal of clinical medicine · 2026Article
- Single-Agent Sedation for Behavioral Management in Pediatric Dentistry: An Umbrella Review of Agents, Routes of Administration, Providers, and Clinical Settings.Children (Basel, Switzerland) · 2026Review
- Assessing Pediatric Sedation Using Patient-Centered Outcomes.Anesthesia progress · 2026Article
- Isfahan Artificial Intelligence Event 2024, Challenge I: Respiratory Depression Detection.Journal of medical signals and sensors · 2026Article
- Retrospective evaluation of intraoperative adverse events among pediatric dental patients undergoing deep sedation: a cross-sectional study.BMC oral health · 2025Observational
- Effect of Midazolam Premedication on Salivary Cortisol Levels in Pediatric Patients with Negative Frankl Behavior: A Pilot Study.Children (Basel, Switzerland) · 2025Article
- The Effect of Music Distraction on Dental Anxiety During Invasive Dental Procedures in Children and Adults: A Meta-Analysis.Journal of clinical medicine · 2024Review
- Modern sedative agents and techniques used in dentistry for patients with special needs: A review.Journal of Taibah University Medical Sciences · 2024Review
- Association between parental factors and child's behaviors during moderate sedation in pediatric dental care.Frontiers in pediatrics · 2024Article
- Predictors of Parental Acceptance towards Contemporary Behavior Management Techniques Used in Pediatric Dentistry: A Preliminary Study on Turkish Population.Children (Basel, Switzerland) · 2023Article
- Changing Trends in Conscious Sedation at Pediatric Dental Offices: A Bibliometric Analysis.Cureus · 2023Review
- Establishment of an intravenous conscious sedation service at a University Dental Clinic in Tanzania.Journal of dental anesthesia and pain medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High levels of dental caries, challenging child behavior, and parent expectations support a need for sedation in pediatric dentistry. This paper reviews modern developments in pediatric sedation with a focus on implementing techniques to enhance success and patient safety. In recent years, sedation for dental procedures has been implicated in a disproportionate number of cases that resulted in death or permanent neurologic damage. The youngest children and those with more complicated medical backgrounds appear to be at greatest risk. To reduce complications, practitioners and regulatory bodies have supported a renewed focus on health care quality and safety. Implementation of high fidelity simulation training and improvements in patient monitoring, including end-tidal carbon dioxide, are becoming recognized as a new standard for sedated patients in dental offices and health care facilities. Safe and appropriate case selection and appropriate dosing for overweight children is also paramount. Oral sedation has been the mainstay of pediatric dental sedation; however, today practitioners are administering modern drugs in new ways with high levels of success. Employing contemporary transmucosal administration devices increases patient acceptance and sedation predictability. While recently there have been many positive developments in sedation technology, it is now thought that medications used in sedation and anesthesia may have adverse effects on the developing brain. The evidence for this is not definitive, but we suggest that practitioners recognize this developing area and counsel patients accordingly. Finally, there is a clear trend of increased use of ambulatory anesthesia services for pediatric dentistry. Today, parents and practitioners have become accustomed to children receiving general anesthesia in the outpatient setting. As a result of these changes, it is possible that dental providers will abandon the practice of personally administering large amounts of sedation to patients, and focus instead on careful case selection for lighter in-office sedation techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.