Evidence map›Paper›PMID 26345156›Full record

ReviewTherapeutics and clinical risk management2015

Apixaban for the prophylaxis and treatment of deep vein thrombosis and pulmonary embolism: an evidence-based review.

Molly W Mandernach, Rebecca J Beyth, Anita Rajasekhar

Open access · goldAbstract readReview
In one paragraph

Review in Therapeutics and clinical risk management, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Comparing Venous Thromboembolism Prophylactic Agents After Hip Fracture Surgery: A National Database Study.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022
    Article
  3. Article
  4. Atraumatic Splenic Rupture on Direct Oral Anticoagulation.Journal of community hospital internal medicine perspectives · 2022
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. [Monitoring of NOAC].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2017
    Article
  11. Quick reference guide to apixaban.Vascular health and risk management · 2017
    Review
  12. Article
  13. Article
  14. Direct oral anticoagulants and venous thromboembolism.European respiratory review : an official journal of the European Respiratory Society · 2016
    Review
  15. Silent but Deadly: A Conservative Approach to Pulmonary Artery Pseudoaneurysm.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Molly W MandernachDivision of Hematology and Oncology, College of Medicine, University of Florida, Gainesville, FL, USA.
Rebecca J BeythDivision of Hematology and Oncology, College of Medicine, University of Florida, Gainesville, FL, USA ; North Florida/South Georgia Veterans Health System (NF/SGVHS), Geriatric Research, Education and Clinical Center (GRECC), Gainesville, FL, USA.
Anita RajasekharDivision of Hematology and Oncology, College of Medicine, University of Florida, Gainesville, FL, USA.
University of Florida · USNorth Florida/South Georgia Veterans Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venous thromboembolism (VTE) results in significant morbidity and mortality. The prevention and treatment of VTE is managed with anticoagulant therapy, historically parenteral anticoagulants such as unfractionated heparin, low molecular weight heparin, and fondaparinux, and oral vitamin K antagonists such as warfarin. In the last few years, several target-specific oral anticoagulants have been developed, including the direct thrombin inhibitor dabigatran and anti-Xa inhibitors rivaroxaban, apixaban, and edoxaban. The target-specific oral anticoagulants have proven to be noninferior to vitamin K antagonists and heparins in the prevention and treatment of VTE. This review will focus on the pharmacology, clinical trial data, and laboratory assessment of apixaban. Moreover, perioperative management, use in special populations, and management of bleeding complications in patients taking apixaban for the prevention and treatment of VTE will also be discussed.

Indexed as

apixabannew oral anticoagulanttarget-specific oral anticoagulantthromboprophylaxisvenous thromboembolism

Identifiers

PMID26345156
PMCPMC4556259
OpenAlexW1524402888

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.